SCHEMBL23908289

SCHEMBL23908289

Cc1cc(Nc2ccccc2)c(Cl)c(Nc2ccccc2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 3/20 0.50
HPGD P15428 2/20 0.50
GAA P10253 6/20 0.48
ALDH1A1 P00352 5/20 0.48
TDP1 Q9NUW8 5/20 0.48
HTT P42858 3/20 0.48
ALOX15 P16050 2/20 0.48
ATM Q13315 2/20 0.45
NPC1 O15118 3/20 0.44
RAB9A P51151 3/20 0.44
GPR35 Q9HC97 1/20 0.44
HSD17B10 Q99714 2/20 0.44
BRD4 O60885 1/20 0.44
BPTF Q12830 1/20 0.44
KAT2B Q92831 1/20 0.44
BRD9 Q9H8M2 1/20 0.44
MAPT P10636 7/20 0.43
MEN1 O00255 7/20 0.43
KMT2A Q03164 7/20 0.43
KDM4E B2RXH2 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25810229 0.90 GAA (0.49) NPSR1HPGDGAAALDH1A1TDP1
SCHEMBL22231911 0.87 GAA (0.50) NPSR1HPGDGAAALDH1A1TDP1
SCHEMBL29454250 0.87 GAA (0.50) NPSR1HPGDGAAALDH1A1TDP1
SCHEMBL23312041 0.82 GAA (0.42) NPSR1HPGDGAAALDH1A1TDP1
SCHEMBL10412855 0.80 HPGD (0.52) NPSR1HPGDGAAALDH1A1TDP1
SCHEMBL30579746 0.79 ALDH1A1 (0.48) NPSR1HPGDGAAALDH1A1TDP1
SCHEMBL19923333 0.78 MAPT (0.62) NPSR1HPGDGAAALDH1A1TDP1
SCHEMBL24237114 0.78 NPSR1 (0.48) NPSR1HPGDGAAALDH1A1TDP1
SCHEMBL23908293 0.77 TSHR (0.43) GAAALDH1A1HTTNPC1RAB9A
SCHEMBL30574526 0.77 RAPGEF4 (0.45) NPSR1GAAALDH1A1RAB9ABRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11845768-B2 Polycyclic compound and organic light-emitting device including same LG CHEM, LTD. (KR) 2023-12-19 US disclosed
CN-112585145-B Polycyclic compound and organic light emitting device including the same 株式会社LG化学 2023-09-29 CN disclosed
CN-113853694-B organic light emitting device 株式会社LG化学 2023-09-05 CN disclosed
US-20230090371-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-03-23 US disclosed
US-20210317147-A1 POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING SAME LG CHEM, LTD. (KR) 2021-10-14 US disclosed
US-20210317147-A1 POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING SAME LG CHEM, LTD. (KR) 2021-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210317147-A1 POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING SAME CYP1A1, CRY1, CYP1B1 NPSR1 3522/4885HPGD 2346/4885GAA 2214/4885
US-11845768-B2 Polycyclic compound and organic light-emitting device including same CRY1, CYP1A1, CRY2 NPSR1 3473/4885HPGD 2441/4885GAA 1737/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.