SCHEMBL23908292

SCHEMBL23908292

CC(C)(C)c1ccc(Nc2cccc(Nc3ccc(C(C)(C)C)cc3-c3ccccc3)c2Cl)c(-c2ccccc2)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.38
ALDH1A1 P00352 3/20 0.38
RAB9A P51151 3/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
CASP3 P42574 2/20 0.38
SENP8 Q96LD8 2/20 0.38
SENP7 Q9BQF6 2/20 0.38
SENP6 Q9GZR1 2/20 0.38
PLA2G1B P04054 1/20 0.38
NFKB1 P19838 1/20 0.38
NFKB2 Q00653 1/20 0.38
RELA Q04206 1/20 0.38
ATG4B Q9Y4P1 1/20 0.38
KCNK18 Q7Z418 1/20 0.37
FABP3 P05413 4/20 0.36
FABP4 P15090 4/20 0.36
MYC P01106 1/20 0.36
MAX P61244 1/20 0.36
FABP5 Q01469 2/20 0.36
GLA P06280 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25629508 0.89 NPC1 (0.46) NPC1ALDH1A1RAB9AL3MBTL1CASP3
SCHEMBL27170178 0.82 MAPT (0.42) NPC1ALDH1A1RAB9AL3MBTL1CASP3
SCHEMBL30814266 0.82 MAPT (0.42) NPC1ALDH1A1RAB9AL3MBTL1CASP3
SCHEMBL26219729 0.82 FADS1 (0.44) ALDH1A1KCNK18ABCG2
SCHEMBL30496501 0.82 FADS1 (0.44) ALDH1A1KCNK18ABCG2
SCHEMBL25120147 0.81 ALDH1A1 (0.44) NPC1ALDH1A1RAB9AL3MBTL1CASP3
SCHEMBL30561839 0.81 ALDH1A1 (0.44) NPC1ALDH1A1RAB9AL3MBTL1CASP3
SCHEMBL30526474 0.81 KCNK18 (0.52) NPC1ALDH1A1RAB9AL3MBTL1CASP3
SCHEMBL22938850 0.81 KCNK18 (0.52) NPC1ALDH1A1RAB9AL3MBTL1CASP3
SCHEMBL30503054 0.80 AKR1C3 (0.46) NPC1ALDH1A1RAB9AL3MBTL1CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11845768-B2 Polycyclic compound and organic light-emitting device including same LG CHEM, LTD. (KR) 2023-12-19 US disclosed
US-20210317147-A1 POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING SAME LG CHEM, LTD. (KR) 2021-10-14 US disclosed
US-20210317147-A1 POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING SAME LG CHEM, LTD. (KR) 2021-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210317147-A1 POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING SAME CYP1A1, CRY1, CYP1B1 NPC1 726/4885ALDH1A1 23/4885RAB9A 2967/4885
US-11845768-B2 Polycyclic compound and organic light-emitting device including same CRY1, CYP1A1, CRY2 NPC1 341/4885ALDH1A1 52/4885RAB9A 2652/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.