Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | FABP3 | P05413 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30561839 | 0.91 | ALDH1A1 (0.44) | NPC1ALDH1A1CASP3RAB9ASENP8 | |
| SCHEMBL25120147 | 0.91 | ALDH1A1 (0.44) | NPC1ALDH1A1CASP3RAB9ASENP8 | |
| SCHEMBL30503054 | 0.90 | AKR1C3 (0.46) | NPC1ALDH1A1CASP3RAB9ASENP8 | |
| SCHEMBL23118189 | 0.90 | AKR1C3 (0.46) | NPC1ALDH1A1CASP3RAB9ASENP8 | |
| SCHEMBL27170178 | 0.89 | MAPT (0.42) | NPC1ALDH1A1CASP3RAB9ASENP8 | |
| SCHEMBL23908292 | 0.89 | NPC1 (0.38) | NPC1ALDH1A1CASP3RAB9ASENP8 | |
| SCHEMBL30814266 | 0.89 | MAPT (0.42) | NPC1ALDH1A1CASP3RAB9ASENP8 | |
| SCHEMBL26485726 | 0.89 | AKR1C3 (0.42) | NPC1ALDH1A1CASP3RAB9ASENP8 | |
| SCHEMBL30980923 | 0.89 | AKR1C3 (0.42) | NPC1ALDH1A1CASP3RAB9ASENP8 | |
| SCHEMBL30526474 | 0.87 | KCNK18 (0.52) | NPC1ALDH1A1CASP3RAB9ASENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11678570-B2 | Hole transport material, preparation method thereof, and electroluminescent device | WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) | 2023-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11678570-B2 | Hole transport material, preparation method thereof, and electroluminescent device | TSPO, NLRP1, NLRP3 | NPC1 498/4885ALDH1A1 2494/4885CASP3 4175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.