Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.37 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 3/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2389438 | 0.84 | MEN1 (0.41) | MEN1KMT2APTGS1PTGS2BCHE | |
| SCHEMBL2389238 | 0.82 | L3MBTL1 (0.46) | MEN1KMT2APTGS1PTGS2BCHE | |
| Oxalic Acid SCHEMBL2390867 | 0.79 | PTGS2 (0.49) | MEN1KMT2APTGS1PTGS2NOS1 | |
| SCHEMBL5013630 | 0.74 | KDM4E (0.48) | NOS1PRMT6BCHEHTR7ALDH1A1 | |
| SCHEMBL9651355 | 0.74 | PTGS1 (0.62) | MEN1KMT2APTGS1PTGS2ALDH1A1 | |
| SCHEMBL16771624 | 0.73 | NOS1 (0.49) | MEN1KMT2ANOS1PRMT6BCHE | |
| SCHEMBL5528738 | 0.73 | SLC7A5 (0.44) | MEN1KMT2ANOS1PRMT6HTR7 | |
| SCHEMBL2917051 | 0.72 | PTGS1 (0.56) | MEN1KMT2APTGS1PTGS2ALDH1A1 | |
| SCHEMBL28499999 | 0.72 | PTGS2 (0.56) | MEN1KMT2APTGS1PTGS2 | |
| SCHEMBL7716765 | 0.72 | PTGS1 (0.56) | MEN1KMT2APTGS1PTGS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8012964-B2 | 9-substituted 8-oxoadenine compound | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2011-09-06 | — | — | US | disclosed |