Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 3/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.38 |
| ▸ | BACE1 | P56817 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2389238 | 0.88 | L3MBTL1 (0.46) | MEN1KMT2APTGS1PTGS2BCHE | |
| SCHEMBL2390872 | 0.84 | MEN1 (0.45) | MEN1KMT2APTGS1PTGS2BCHE | |
| Oxalic Acid SCHEMBL2389436 | 0.82 | PTGS1 (0.44) | MEN1KMT2APTGS1PTGS2BCHE | |
| SCHEMBL13999438 | 0.79 | BACE1 (0.50) | BCHEPDCD1CD274BACE1CTSD | |
| SCHEMBL5528751 | 0.74 | SLC7A5 (0.42) | MEN1KMT2APDCD1CD274KDM4E | |
| SCHEMBL28519935 | 0.73 | BCHE (0.50) | MEN1KMT2ABCHEPDCD1CD274 | |
| SCHEMBL10859843 | 0.72 | PDCD1 (0.53) | MEN1KMT2APDCD1CD274VSIR | |
| Oxalic Acid SCHEMBL2389235 | 0.71 | MEN1 (0.47) | MEN1KMT2APTGS1KDM4ECYP2C9 | |
| SCHEMBL27664420 | 0.71 | BCHE (0.50) | MEN1KMT2ABCHEBACE1 | |
| SCHEMBL28499999 | 0.71 | PTGS2 (0.56) | MEN1KMT2APTGS1PTGS2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8012964-B2 | 9-substituted 8-oxoadenine compound | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2011-09-06 | — | — | US | disclosed |