Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28918928 | 0.85 | PDE2A (0.47) | PDE2AALDH1A1MAPTAHRPPARD | |
| SCHEMBL20072565 | 0.82 | PDE2A (0.44) | PDE2AALDH1A1MAPTAHRPPARD | |
| SCHEMBL20256180 | 0.79 | PDE2A (0.42) | PDE2AALDH1A1MAPTPPARDMRGPRX4 | |
| SCHEMBL18681063 | 0.75 | IDO1 (0.41) | PDE2AAHRTSHRMEN1KMT2A | |
| SCHEMBL29402881 | 0.75 | TSHR (0.61) | PDE2AALDH1A1MAPTAHRTSHR | |
| SCHEMBL980201 | 0.75 | TSHR (0.61) | PDE2AALDH1A1MAPTAHRTSHR | |
| SCHEMBL11265653 | 0.73 | PDE7A (0.45) | PDE2AALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL19785361 | 0.73 | PDE2A (0.52) | PDE2AALDH1A1MAPTAHRTSHR | |
| Ammonia Solution, Strong SCHEMBL28020319 | 0.73 | TSHR (0.58) | PDE2AALDH1A1MAPTAHRTSHR | |
| SCHEMBL1040760 | 0.71 | CES2 (0.50) | PDE2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3094325-B1 | HETEROARYLS AND USES THEREOF | TAKEDA PHARMACEUTICALS CO (JP) | 2021-10-13 | — | — | EP | disclosed |