Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | UGCG | Q16739 | 5/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | GALR3 | O60755 | 1/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23912947 | 0.85 | ADRA1D (0.38) | PDK2ALDH1A1UGCGKDM4EADRA1D | |
| SCHEMBL23904672 | 0.83 | KDM4E (0.40) | PDK2ALDH1A1KDM4EADRA1DADRA1A | |
| SCHEMBL23904670 | 0.83 | KDM4E (0.40) | PDK2ALDH1A1KDM4EADRA1DADRA1A | |
| SCHEMBL23912942 | 0.83 | TSHR (0.37) | PDK2TSHRALDH1A1MAPTUGCG | |
| SCHEMBL4281260 | 0.71 | GAA (0.46) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL23904676 | 0.70 | KDM4E (0.38) | ALDH1A1KDM4EADRA1DADRA1AADRA1B | |
| SCHEMBL23904673 | 0.70 | KDM4E (0.38) | ALDH1A1KDM4EADRA1DADRA1AADRA1B | |
| SCHEMBL23912884 | 0.68 | LMNA (0.42) | PDK2ALDH1A1MAPTUGCGKDM4E | |
| SCHEMBL8543244 | 0.67 | ADRA1D (0.45) | ADRA1DADRA1AADRA1B | |
| SCHEMBL7902963 | 0.67 | ADRA1D (0.45) | ADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892615-A1 | PROCESS FOR THE PREPARATION OF SILODOSIN | Minakem (FR) | 2021-10-13 | — | — | EP | disclosed |