Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.36 |
| ▸ | RBP4 | P02753 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | PTGIR | P43119 | 1/20 | 0.34 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23904676 | 1.00 | KDM4E (0.38) | KDM4EALDH1A1TDP1PTGDR2RBP4 | |
| SCHEMBL23904670 | 0.85 | KDM4E (0.40) | KDM4EALDH1A1TDP1RBP4LMNA | |
| SCHEMBL23904672 | 0.85 | KDM4E (0.40) | KDM4EALDH1A1TDP1RBP4LMNA | |
| SCHEMBL23912947 | 0.76 | ADRA1D (0.38) | KDM4EALDH1A1RBP4ADRA1DADRA1A | |
| SCHEMBL23904679 | 0.70 | ADRA1A (0.53) | KDM4EALDH1A1TDP1LMNAADRA1D | |
| SCHEMBL23904680 | 0.70 | ADRA1A (0.53) | KDM4EALDH1A1TDP1LMNAADRA1D | |
| SCHEMBL23912941 | 0.70 | PDK2 (0.34) | KDM4EALDH1A1ADRA1DADRA1AADRA1B | |
| SCHEMBL18285962 | 0.68 | HTT (0.45) | ALDH1A1LMNAABCB1 | |
| SCHEMBL12130679 | 0.67 | KMT2A (0.50) | ALDH1A1TDP1LMNAABCB1 | |
| SCHEMBL18154139 | 0.67 | ALDH1A1 (0.49) | ALDH1A1TDP1LMNAABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892615-A1 | PROCESS FOR THE PREPARATION OF SILODOSIN | Minakem (FR) | 2021-10-13 | — | — | EP | claimed |