Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | UGCG | Q16739 | 2/20 | 0.34 |
| ▸ | RBP4 | P02753 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23904670 | 0.90 | KDM4E (0.40) | ADRA1DADRA1AADRA1BKDM4EALDH1A1 | |
| SCHEMBL23904672 | 0.90 | KDM4E (0.40) | ADRA1DADRA1AADRA1BKDM4EALDH1A1 | |
| SCHEMBL23912941 | 0.85 | PDK2 (0.34) | ADRA1DADRA1AADRA1BKDM4EALDH1A1 | |
| SCHEMBL23904676 | 0.76 | KDM4E (0.38) | ADRA1DADRA1AADRA1BKDM4EALDH1A1 | |
| SCHEMBL23904673 | 0.76 | KDM4E (0.38) | ADRA1DADRA1AADRA1BKDM4EALDH1A1 | |
| SCHEMBL23912884 | 0.75 | LMNA (0.42) | KDM4EALDH1A1PDK2MEN1KMT2A | |
| SCHEMBL23912946 | 0.74 | ADRA1A (0.54) | ADRA1DADRA1AADRA1BKDM4EALDH1A1 | |
| SCHEMBL21385385 | 0.72 | MEN1 (0.40) | MEN1KMT2A | |
| SCHEMBL17881260 | 0.72 | MEN1 (0.40) | MEN1KMT2A | |
| SCHEMBL8543244 | 0.72 | ADRA1D (0.45) | ADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892615-A1 | PROCESS FOR THE PREPARATION OF SILODOSIN | Minakem (FR) | 2021-10-13 | — | — | EP | disclosed |