Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.35 |
| ▸ | UGCG | Q16739 | 5/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 5/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23912941 | 0.83 | PDK2 (0.34) | TSHRPDK2UGCGHCRTR1HCRTR2 | |
| SCHEMBL23912884 | 0.82 | LMNA (0.42) | PDK2UGCGHCRTR1HCRTR2ALDH1A1 | |
| SCHEMBL14238192 | 0.69 | GAA (0.43) | ALDH1A1 | |
| SCHEMBL31054935 | 0.68 | PDK2 (0.38) | PDK2ALDH1A1MAPT | |
| SCHEMBL23912947 | 0.68 | ADRA1D (0.38) | PDK2UGCGHCRTR1HCRTR2ALDH1A1 | |
| SCHEMBL23904672 | 0.68 | KDM4E (0.40) | PDK2HCRTR1HCRTR2ALDH1A1KDM4E | |
| SCHEMBL23904670 | 0.68 | KDM4E (0.40) | PDK2HCRTR1HCRTR2ALDH1A1KDM4E | |
| SCHEMBL23923224 | 0.67 | KMT2A (0.35) | — | |
| SCHEMBL30278711 | 0.67 | KMT2A (0.35) | — | |
| SCHEMBL14234032 | 0.67 | GAA (0.43) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892615-A1 | PROCESS FOR THE PREPARATION OF SILODOSIN | Minakem (FR) | 2021-10-13 | — | — | EP | disclosed |