Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | TEAD3 | Q99594 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23904669 | 0.87 | CTSL (0.37) | HRH3CTSLCTSBCTSKTEAD3 | |
| SCHEMBL3341412 | 0.87 | CTSL (0.37) | HRH3CTSLCTSBCTSKTEAD3 | |
| SCHEMBL15934399 | 0.87 | HRH3 (0.36) | L3MBTL1HRH3CTSLCTSBCTSK | |
| SCHEMBL16749903 | 0.86 | ADRA1D (0.41) | HRH3CTSLCTSBCTSKTEAD3 | |
| SCHEMBL4537574 | 0.85 | TEAD3 (0.39) | HRH3CTSLCTSBCTSKTEAD3 | |
| SCHEMBL3342398 | 0.84 | TEAD3 (0.39) | HRH3TEAD3ALDH1A1ADRA1DADRA1A | |
| SCHEMBL12247877 | 0.84 | ADRA1D (0.42) | HRH3CTSLCTSBCTSKTEAD3 | |
| SCHEMBL17502988 | 0.84 | ADRA1D (0.42) | HRH3CTSLCTSBCTSKTEAD3 | |
| SCHEMBL16749902 | 0.82 | ADRA1D (0.44) | TEAD3ADRA1DADRA1AADRA1BMEN1 | |
| SCHEMBL12816498 | 0.82 | ADRA1D (0.44) | TEAD3ADRA1DADRA1AADRA1BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892615-A1 | PROCESS FOR THE PREPARATION OF SILODOSIN | Minakem (FR) | 2021-10-13 | — | — | EP | disclosed |