Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11134511 | 0.94 | ALDH1A1 (0.47) | ALDH1A1PARP10SMN1; SMN2PPARGPPARA | |
| SCHEMBL97898 | 0.87 | PARP10 (0.48) | ALDH1A1PARP10KMT2ALMNAPOLB | |
| SCHEMBL10977168 | 0.87 | PARP10 (0.48) | ALDH1A1PARP10KMT2ALMNAPOLB | |
| SCHEMBL17961880 | 0.87 | PARP10 (0.48) | ALDH1A1PARP10KMT2ALMNAPOLB | |
| SCHEMBL9814077 | 0.80 | CYP1A2 (0.50) | PARP10SMN1; SMN2PPARGPPARAKMT2A | |
| SCHEMBL105035 | 0.80 | ALDH1A3 (0.52) | ALDH1A1PARP10SMN1; SMN2KMT2AMAPT | |
| SCHEMBL4071188 | 0.79 | ALDH1A1 (0.50) | ALDH1A1PARP10SMN1; SMN2PPARGPPARA | |
| SCHEMBL6061597 | 0.78 | ESR2 (0.48) | ALDH1A1PARP10KMT2AMAPTMEN1 | |
| SCHEMBL29619678 | 0.78 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2PPARGPPARAKMT2A | |
| SCHEMBL7521294 | 0.78 | ACHE (0.46) | ALDH1A1PARP10PPARGPPARAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11142512-B2 | Nebivolol synthesis method and intermediate compound thereof | ZHEJIANG AUSUN PHARMACEUTICAL CO., LTD. (CN) | 2021-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11142512-B2 | Nebivolol synthesis method and intermediate compound thereof | CYP4A11, CYP11B2, ADRB1 | ALDH1A1 401/4885PARP10 768/4885SMN1; SMN2 3833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.