SCHEMBL2391371

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5065346	0.85	CASP1 (0.49)	CXCL8CASP1AOC3ALDH1A1
	SCHEMBL5065343	0.85	CASP1 (0.49)	CXCL8CASP1AOC3ALDH1A1
	SCHEMBL2390308	0.83	OPRL1 (0.38)	KMT2AATMGRM2
	SCHEMBL2393152	0.79	CES2 (0.46)	PARP1SLC9A1KMT2AGRM2MEN1
	SCHEMBL9890698	0.78	CASP1 (0.44)	HSD17B10CASP1KMT2AALDH1A1NPSR1
	SCHEMBL2393200	0.78	APP (0.43)	PTPRCIKBKBSLC9A1
	SCHEMBL2393198	0.78	APP (0.43)	PTPRCIKBKBSLC9A1
	SCHEMBL2391614	0.78	APP (0.43)	PTPRCIKBKBSLC9A1
	SCHEMBL2392699	0.78	BCAT2 (0.55)	HSD17B10KMT2AMEN1ALDH1A1
	SCHEMBL2395264	0.78	BCAT2 (0.55)	HSD17B10KMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.