Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | ACP3 | P15309 | 1/20 | 0.42 |
| ▸ | GLS | O94925 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | TDO2 | P48775 | 2/20 | 0.40 |
| ▸ | IDO2 | Q6ZQW0 | 2/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5065346 | 1.00 | CASP1 (0.49) | CASP1CXCL8AOC3ACP3GLS | |
| SCHEMBL2391371 | 0.85 | CXCL8 (0.41) | CASP1CXCL8AOC3ALDH1A1 | |
| SCHEMBL9518776 | 0.83 | CXCL8 (0.47) | CASP1CXCL8AOC3ACP3ADRB2 | |
| SCHEMBL29398319 | 0.81 | LMNA (0.52) | CASP1CXCL8AOC3ACP3GLS | |
| SCHEMBL24732 | 0.81 | LMNA (0.52) | CASP1CXCL8AOC3ACP3GLS | |
| SCHEMBL197618 | 0.81 | LMNA (0.52) | CASP1CXCL8AOC3ACP3GLS | |
| SCHEMBL24733 | 0.81 | LMNA (0.52) | CASP1CXCL8AOC3ACP3GLS | |
| SCHEMBL29501895 | 0.81 | LMNA (0.52) | CASP1CXCL8AOC3ACP3GLS | |
| SCHEMBL29465008 | 0.81 | LMNA (0.52) | CASP1CXCL8AOC3ACP3GLS | |
| SCHEMBL23300492 | 0.79 | CXCL8 (0.45) | CASP1CXCL8AOC3ACP3IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050202545-A1 | Methods for producing optically active alpha-hydroxy amides | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2005-09-15 | — | — | US | claimed |
| US-20080261286-A1 | Methods for producing optically active alpha-hydroxy amides | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2008-10-23 | — | — | US | disclosed |
| US-20080261286-A1 | Methods for producing optically active alpha-hydroxy amides | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2008-10-23 | — | — | US | disclosed |
| US-20050202545-A1 | Methods for producing optically active alpha-hydroxy amides | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2005-09-15 | — | — | US | disclosed |
| US-20050202545-A1 | Methods for producing optically active alpha-hydroxy amides | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2005-09-15 | — | — | US | disclosed |
| JP-2005218348-A | METHOD FOR PRODUCING OPTICALLY ACTIVE α-HYDROXY AMIDE | DAICEL CHEM IND LTD | 2005-08-18 | — | — | JP | disclosed |