SCHEMBL23913889

SCHEMBL23913889

CN(N)/C(=N\N)NC(=O)c1ccnc(Cl)c1Cl

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SLC6A9 P48067 1/20 0.34
EGFR P00533 2/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
HPGD P15428 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
ATR Q13535 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
MEN1 O00255 1/20 0.31
NPC1 O15118 1/20 0.31
POLB P06746 1/20 0.31
RAB9A P51151 1/20 0.31
KMT2A Q03164 1/20 0.31
HTT P42858 1/20 0.30
P2RX7 Q99572 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22245656 0.90 P2RX7 (0.35) L3MBTL1P2RX7
SCHEMBL23914139 0.81 CDK2 (0.33) EGFRNPC1RAB9A
SCHEMBL22245632 0.80 KDM4E (0.30) LMNAPOLB
SCHEMBL22918688 0.73 CTSS (0.35) ALDH1A1SMN1; SMN2RAB9A
SCHEMBL19979960 0.73 TUBB4A (0.38) EGFRLMNANPC1RAB9AP2RX7
SCHEMBL23913851 0.72 MAPK14 (0.33) LMNANPC1RAB9A
SCHEMBL6180683 0.72 CASP1 (0.45) SLC6A9EGFRALDH1A1LMNAHPGD
SCHEMBL16523551 0.67 ATR (0.36) SLC6A9EGFRALDH1A1LMNAHPGD
SCHEMBL30961407 0.66 SMN1; SMN2 (0.42) SLC6A9ALDH1A1LMNAHPGDSMN1; SMN2
SCHEMBL1760077 0.66 KDM4E (0.43) ALDH1A1LMNASMN1; SMN2ATRL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3892618-A1 4-PYRIDINYL FORMAMIDE COMPOUND OR DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF Qingdao KingAgroot Chemical Compound Co., Ltd. (CN) 2021-10-13 EP disclosed