SCHEMBL239140

SCHEMBL239140

CC[O-].C[N+](C)(C)c1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APOBEC3A P31941 1/20 0.70
APOBEC3G Q9HC16 1/20 0.70
ACHE P22303 5/20 0.39
TP53 P04637 2/20 0.38
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
TSHR P16473 1/20 0.34
OPRM1 P35372 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
BLM P54132 1/20 0.33
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
DNM1 Q05193 2/20 0.32
ALPL P05186 1/20 0.32
POLB P06746 1/20 0.32
ALPG P10696 1/20 0.32
PSIP1 O75475 1/20 0.32
MEN1 O00255 1/20 0.31
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5164341 0.97 APOBEC3A (0.67) APOBEC3AAPOBEC3GACHETP53KDM4E
SCHEMBL2385111 0.86 APOBEC3A (0.82) APOBEC3AAPOBEC3GACHETP53KDM4E
SCHEMBL12020269 0.86 APOBEC3A (0.93) APOBEC3AAPOBEC3GACHETP53KDM4E
SCHEMBL147815 0.86 APOBEC3A (0.93) APOBEC3AAPOBEC3GACHETP53KDM4E
Alcohol SCHEMBL27837339 0.84 APOBEC3A (0.70) APOBEC3AAPOBEC3GACHETP53KDM4E
Bromide SCHEMBL10995909 0.83 APOBEC3A (0.88) APOBEC3AAPOBEC3GACHETP53KDM4E
Water SCHEMBL35582 0.83 APOBEC3A (0.88) APOBEC3AAPOBEC3GACHETP53KDM4E
Bromide SCHEMBL80469 0.83 APOBEC3A (0.88) APOBEC3AAPOBEC3GACHETP53KDM4E
SCHEMBL7546894 0.83 APOBEC3A (0.88) APOBEC3AAPOBEC3GACHETP53KDM4E
Bromide SCHEMBL238552 0.83 APOBEC3A (0.88) APOBEC3AAPOBEC3GACHETP53KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3330311-B1 STORAGE STABLE 1K-POLYURETHANE-PREPREGS AND MOULDED ARTICLE MADE FROM SAME ON THE BASIS OF A POLYURETHANE COMPOSITION EVONIK OPERATIONS GMBH (DE) 2021-05-05 EP claimed
US-10633519-B2 Storage-stable polyurethane prepregs and mouldings produced therefrom composed of a polyurethane composition with liquid resin components EVONIK OPERATIONS GMBH (DE) 2020-04-28 US claimed
US-10626236-B2 Storage-stable one-component polyurethane prepregs and shaped bodies composed of polyurethane composition that have been produced therefrom EVONIK OPERATIONS GMBH (DE) 2020-04-21 US claimed
US-20180155515-A1 STORAGE-STABLE ONE-COMPONENT POLYURETHANE PREPREGS AND SHAPED BODIES COMPOSED OF POLYURETHANE COMPOSITION THAT HAVE BEEN PRODUCED THEREFROM EVONIK OPERATIONS GMBH (DE) 2018-06-07 US claimed
EP-2411439-B1 PREPEGS AND MOLDED BODIES PRODUCED THEREOF AT LOW TEMPERATURE EVONIK DEGUSSA GMBH (DE) 2016-11-16 EP claimed
EP-2188320-B1 DUAL CURE FORMULATIONS WITH COMPONENTS COMPRISING URETDIONE GROUPS EVONIK DEGUSSA GMBH (DE) 2014-05-14 EP claimed
US-20140087613-A1 STORAGE-STABLE POLYURETHANE PREPREGS AND MOULDINGS PRODUCED THEREFROM COMPOSED OF A POLYURETHANE COMPOSITION WITH LIQUID RESIN COMPONENTS EVONIK DEGUSSA GMBH (DE) 2014-03-27 US claimed
US-8455090-B2 Prepegs and molded bodies produced thereof at low temperature EVONIK DEGUSSA GMBH (DE) 2013-06-04 US claimed
US-20120003890-A1 PREPEGS AND MOLDED BODIES PRODUCED THEREOF AT LOW TEMPERATURE EVONIK DEGUSSA GMBH (DE) 2012-01-05 US claimed
US-20110224458-A1 PREPARATION OF METHIONINE OR SELENOMETHIONINE FROM HOMOSERINE VIA A 4-SUBSTITUTED 2-AMINOBUTANOIC ACID INTERMEDIATE NOVUS INTERNATIONAL INC. (US) 2011-09-15 US claimed
US-20100227942-A1 DUAL-CURE FORMULATIONS WITH COMPONENTS CONTAINING URETDIONE GROUPS EVONIK DEGUSSA GMBH (DE) 2010-09-09 US claimed
EP-1560833-B1 PREPARATION OF CODEINE FROM MORPHINE MALLINCKRODT INTERNAT CORP (US) 2007-03-14 EP claimed
EP-1560833-A2 PREPARATION OF CODEINE FROM MORPHINE Mallinckrodt International Corporation (US) 2005-08-10 EP claimed
WO-2004037826-A2 PREPARATION OF CODEINE FROM MORPHINE MALLINCKRODT INC. (US) 2004-05-06 WO claimed
US-6579985-B1 Preparation of codeine from morphine MALLINCKRODT INC. 2003-06-17 US claimed
US-10793664-B2 Process for preparing trimers and/or oligomers of diisocyanates EVONIK OPERATIONS GMBH (DE) 2020-10-06 US disclosed
US-10633519-B2 Storage-stable polyurethane prepregs and mouldings produced therefrom composed of a polyurethane composition with liquid resin components EVONIK OPERATIONS GMBH (DE) 2020-04-28 US disclosed
EP-0268710-B1 IMPROVED PROCESS FOR THE PREPARATION OF CODEINE FROM MORPHINE Council of Scientific and Industrial Research (IN) 1991-05-15 EP disclosed
US-4764615-A Process for the preparation of codeine from morphine COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 1988-08-16 US disclosed
EP-0268710-A1 Improved process for the preparation of codeine from morphine Council of Scientific and Industrial Research (IN) 1988-06-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224458-A1 PREPARATION OF METHIONINE OR SELENOMETHIONINE FROM HOMOSERINE VIA A 4-SUBSTITUTED 2-AMINOBUTANOIC ACID INTERMEDIATE MTR, CBS, ABAT APOBEC3A 3356/4885APOBEC3G 3619/4885ACHE 4455/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.