Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3A | P31941 | 1/20 | 0.82 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.82 |
| ▸ | ACHE | P22303 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 3/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ALPG | P10696 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL147815 | 0.94 | APOBEC3A (0.93) | APOBEC3AAPOBEC3GACHEALDH1A1TDP1 | |
| SCHEMBL12020269 | 0.94 | APOBEC3A (0.93) | APOBEC3AAPOBEC3GACHEALDH1A1TDP1 | |
| Bromide SCHEMBL238552 | 0.90 | APOBEC3A (0.88) | APOBEC3AAPOBEC3GACHEALDH1A1TDP1 | |
| Bromide SCHEMBL80469 | 0.90 | APOBEC3A (0.88) | APOBEC3AAPOBEC3GACHEALDH1A1TDP1 | |
| Iodide SCHEMBL238393 | 0.90 | APOBEC3A (1.00) | APOBEC3AAPOBEC3GACHEALDH1A1TDP1 | |
| Water SCHEMBL35582 | 0.90 | APOBEC3A (0.88) | APOBEC3AAPOBEC3GACHEALDH1A1TDP1 | |
| SCHEMBL7546894 | 0.90 | APOBEC3A (0.88) | APOBEC3AAPOBEC3GACHEALDH1A1TDP1 | |
| Bromide SCHEMBL10995909 | 0.90 | APOBEC3A (0.88) | APOBEC3AAPOBEC3GACHEALDH1A1TDP1 | |
| SCHEMBL7546898 | 0.90 | APOBEC3A (0.88) | APOBEC3AAPOBEC3GACHEALDH1A1TDP1 | |
| Bromide SCHEMBL3899566 | 0.90 | APOBEC3A (0.88) | APOBEC3AAPOBEC3GACHEALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3330311-B1 | STORAGE STABLE 1K-POLYURETHANE-PREPREGS AND MOULDED ARTICLE MADE FROM SAME ON THE BASIS OF A POLYURETHANE COMPOSITION | EVONIK OPERATIONS GMBH (DE) | 2021-05-05 | — | — | EP | claimed |
| US-10626236-B2 | Storage-stable one-component polyurethane prepregs and shaped bodies composed of polyurethane composition that have been produced therefrom | EVONIK OPERATIONS GMBH (DE) | 2020-04-21 | — | — | US | claimed |
| US-20180155515-A1 | STORAGE-STABLE ONE-COMPONENT POLYURETHANE PREPREGS AND SHAPED BODIES COMPOSED OF POLYURETHANE COMPOSITION THAT HAVE BEEN PRODUCED THEREFROM | EVONIK OPERATIONS GMBH (DE) | 2018-06-07 | — | — | US | claimed |
| US-20110224458-A1 | PREPARATION OF METHIONINE OR SELENOMETHIONINE FROM HOMOSERINE VIA A 4-SUBSTITUTED 2-AMINOBUTANOIC ACID INTERMEDIATE | NOVUS INTERNATIONAL INC. (US) | 2011-09-15 | — | — | US | claimed |
| US-10793664-B2 | Process for preparing trimers and/or oligomers of diisocyanates | EVONIK OPERATIONS GMBH (DE) | 2020-10-06 | — | — | US | disclosed |
| US-10626236-B2 | Storage-stable one-component polyurethane prepregs and shaped bodies composed of polyurethane composition that have been produced therefrom | EVONIK OPERATIONS GMBH (DE) | 2020-04-21 | — | — | US | disclosed |
| US-10336856-B2 | Alkoxysilane- and allophanate-functionalized coating materials | EVONIK DEGUSSA GMBH (DE) | 2019-07-02 | — | — | US | disclosed |
| US-20180327538-A1 | PROCESS FOR PREPARING TRIMERS AND/OR OLIGOMERS OF DIISOCYANATES | EVONIK OPERATIONS GMBH (DE) | 2018-11-15 | — | — | US | disclosed |
| US-20180312713-A1 | Coating compositions comprising monoallophanates based on alkoxysilane alkyl isocyanates | EVONIK DEGUSSA GMBH (DE) | 2018-11-01 | — | — | US | disclosed |
| US-10093826-B2 | Alkoxysilane-functionalized allophanate-containing coating compositions | EVONIK DEGUSSA GMBH (DE) | 2018-10-09 | — | — | US | disclosed |
| US-20180155515-A1 | STORAGE-STABLE ONE-COMPONENT POLYURETHANE PREPREGS AND SHAPED BODIES COMPOSED OF POLYURETHANE COMPOSITION THAT HAVE BEEN PRODUCED THEREFROM | EVONIK OPERATIONS GMBH (DE) | 2018-06-07 | — | — | US | disclosed |
| US-9902095-B2 | Production of fibre composite component part based on steel and polyurethane | EVONIK DEGUSSA GMBH (DE) | 2018-02-27 | — | — | US | disclosed |
| US-20150321393-A1 | PRODUCTION OF FIBRE COMPOSITE COMPONENT PART BASED ON ALUMINIUM AND POLYURETHANE | EVONIK INDUSTRIES AG (DE) | 2015-11-12 | — | — | US | disclosed |
| US-8742170-B2 | Preparation of methionine or selenomethionine from homoserine via a 4-substituted 2-aminobutanoic acid intermediate | NOVUS INTERNATIONAL, INC. (US) | 2014-06-03 | — | — | US | disclosed |
| US-20110224458-A1 | PREPARATION OF METHIONINE OR SELENOMETHIONINE FROM HOMOSERINE VIA A 4-SUBSTITUTED 2-AMINOBUTANOIC ACID INTERMEDIATE | NOVUS INTERNATIONAL INC. (US) | 2011-09-15 | — | — | US | disclosed |
| WO-2010118274-A1 | PREPARATION OF 6-KETO, 3-ALKOXY MORPHINANS | MALLINCKRODT INC. (US) | 2010-10-14 | — | — | WO | disclosed |
| US-20100261906-A1 | Preparation of 6-Keto, 3-Alkoxy Morphinans | MALLINCKRODT INC. (US) | 2010-10-14 | — | — | US | disclosed |
| US-6972332-B1 | Process for the production of opiates | ACURA PHARMACEUTICALS, INC. (US) | 2005-12-06 | — | — | US | disclosed |
| US-20050261500-A1 | PROCESS FOR THE PRODUCTION OF OPIATES | SCHUTTE, JOHN | 2005-11-24 | — | — | US | disclosed |
| US-6949645-B1 | Process for the production of opiates | ACURA PHARMACEUTICALS, INC. (US) | 2005-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10336856-B2 | Alkoxysilane- and allophanate-functionalized coating materials | DDAH1, OR10J3, AP3S1 | APOBEC3A 1140/4885APOBEC3G 1858/4885ACHE 4525/4885 |
| US-10093826-B2 | Alkoxysilane-functionalized allophanate-containing coating compositions | DDAH1, OR10J3, AP3S1 | APOBEC3A 1329/4885APOBEC3G 2317/4885ACHE 4103/4885 |
| US-20100261906-A1 | Preparation of 6-Keto, 3-Alkoxy Morphinans | FASN, CYP2D6, CYP2B6 | APOBEC3A 438/4885APOBEC3G 331/4885ACHE 935/4885 |
| US-20050261500-A1 | PROCESS FOR THE PRODUCTION OF OPIATES | OPRM1, OPRK1, POP1 | APOBEC3A 2802/4885APOBEC3G 3135/4885ACHE 11/4885 |
| US-20110224458-A1 | PREPARATION OF METHIONINE OR SELENOMETHIONINE FROM HOMOSERINE VIA A 4-SUBSTITUTED 2-AMINOBUTANOIC ACID INTERMEDIATE | MTR, CBS, ABAT | APOBEC3A 3356/4885APOBEC3G 3619/4885ACHE 4455/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.