Known targets — ChEMBL curated mechanism
GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3A | P31941 | 1/20 | 0.88 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.88 |
| ▸ | ACHE | P22303 | 8/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | CA3 | P07451 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphine SCHEMBL27465237 | 0.97 | APOBEC3A (0.82) | APOBEC3AAPOBEC3GACHEALDH1A1TDP1 | |
| Water SCHEMBL28744902 | 0.97 | APOBEC3A (0.82) | APOBEC3AAPOBEC3GACHEALDH1A1TDP1 | |
| SCHEMBL12020269 | 0.97 | APOBEC3A (0.93) | APOBEC3AAPOBEC3GACHEALDH1A1TDP1 | |
| SCHEMBL147815 | 0.97 | APOBEC3A (0.93) | APOBEC3AAPOBEC3GACHEALDH1A1TDP1 | |
| Water SCHEMBL27482461 | 0.94 | APOBEC3A (0.78) | APOBEC3AAPOBEC3GACHEALDH1A1TDP1 | |
| Methyl Alcohol SCHEMBL27917656 | 0.94 | APOBEC3A (0.78) | APOBEC3AAPOBEC3GACHEALDH1A1TDP1 | |
| Bromide SCHEMBL238552 | 0.93 | APOBEC3A (0.88) | APOBEC3AAPOBEC3GACHEALDH1A1TDP1 | |
| Iodide SCHEMBL238393 | 0.93 | APOBEC3A (1.00) | APOBEC3AAPOBEC3GACHEALDH1A1TDP1 | |
| Bromide SCHEMBL10995909 | 0.93 | APOBEC3A (0.88) | APOBEC3AAPOBEC3GACHEALDH1A1TDP1 | |
| Bromide SCHEMBL80469 | 0.93 | APOBEC3A (0.88) | APOBEC3AAPOBEC3GACHEALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3465 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12291655-B2 | Polishing composition and method of polishing a substrate having enhanced defect reduction | DuPont Electronic Materials Holding, Inc. (US) | 2025-05-06 | — | — | US | claimed |
| US-20250096297-A1 | NOVEL AQUEOUS-PHASE REDOX FLOW BATTERIES | UNIVERSITE DE RENNES (FR) | 2025-03-20 | — | — | US | claimed |
| CN-119574744-A | Method for rapidly determining volatile organic acid in electronic atomized liquid | 东莞市鸿馥生物科技有限公司 | 2025-03-07 | — | — | CN | claimed |
| US-20250066968-A1 | METHOD FOR DEGUMMING AND DECOLORIZING POLYESTER FABRIC | NAN YA PLASTICS CORPORATION (TW) | 2025-02-27 | — | — | US | claimed |
| CN-119507194-A | Method for removing glue and decoloring polyester fabric | 南亚塑胶工业股份有限公司 | 2025-02-25 | — | — | CN | claimed |
| CN-119490194-A | Method for synthesizing CHA molecular sieve from coal gangue | 中国科学院大连化学物理研究所 | 2025-02-21 | — | — | CN | claimed |
| CN-119489188-A | Preparation method of few-layer MXene coated titanium composite powder | 中国科学院过程工程研究所 | 2025-02-21 | — | — | CN | claimed |
| CN-119199141-A | Sweetener thermal cracking analysis method and application thereof | 东莞市鸿馥生物科技有限公司 | 2024-12-27 | — | — | CN | claimed |
| CN-119126507-A | Photoresist stripping liquid, preparation method and application thereof | 浙江奥首材料科技有限公司 | 2024-12-13 | — | — | CN | claimed |
| EP-4470056-A1 | NOVEL AQUEOUS-PHASE REDOX FLOW BATTERIES | Kemiwatt (FR) | 2024-12-04 | — | — | EP | claimed |
| EP-0364895-A1 | Positive type photoresist developer | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1990-04-25 | — | — | EP | claimed |
| CN-1040572-A | The preparation method and the goods thereof of pottery | GRACE W R & CO (US) | 1990-03-21 | — | — | CN | claimed |
| EP-0355252-A2 | Manufacturing method for ceramics and products thereof | W.R. Grace & Co.-Conn. (US) | 1990-02-28 | — | — | EP | claimed |
| CN-1031829-A | The production method of superconducting ceramics and products thereof | GRACE W R & CO (US) | 1989-03-22 | — | — | CN | claimed |
| EP-0306973-A2 | Manufacturing method for superconducting ceramics and products thereof | W.R. Grace & Co.-Conn. (US) | 1989-03-15 | — | — | EP | claimed |
| US-4744834-A | Photoresist stripper comprising a pyrrolidinone, a diethylene glycol ether, a polyglycol and a quaternary ammonium hydroxide | VERSUM MATERIALS US, LLC | 1988-05-17 | — | — | US | claimed |
| US-4377529-A | CHEMICAL INTERMEDIATES IN PRODUCTION OF NICKEL YLIDE CATALYSTS FOR OLIGOMERIZATION OF ETHYLENE | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1983-03-22 | — | — | US | claimed |
| EP-0052929-A1 | Sulfonated group VA ylides and process for preparing same | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1982-06-02 | — | — | EP | claimed |
| EP-0046628-A2 | Process for the preparation of nickel ylides containing directly sulfonated ylide ligands | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1982-03-03 | — | — | EP | claimed |
| EP-0042659-A1 | 5,6,6a,7-Tetrahydro-4H-dibenz(de,g)isoquinoline derivatives, process for their preparation and pharmaceutical compositions containing them | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1981-12-30 | — | — | EP | claimed |