Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.49 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 9/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22494221 | 0.90 | RAB9A (0.62) | OXTRRAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL14804396 | 0.85 | ALDH1A1 (0.47) | RAB9ANPC1AVPR1AMAPTALDH1A1 | |
| SCHEMBL1104413 | 0.81 | RAB9A (0.51) | OXTRRAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL13827863 | 0.79 | OXTR (0.58) | OXTRRAB9ANPC1AVPR2AVPR1A | |
| SCHEMBL10915111 | 0.79 | ALDH1A1 (0.66) | RAB9ANPC1MAPTALDH1A1TDP1 | |
| SCHEMBL10916689 | 0.78 | SCN5A (0.55) | OXTRRAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL14076996 | 0.76 | ALDH1A1 (0.47) | RAB9ANPC1AVPR1AALDH1A1TDP1 | |
| SCHEMBL24484316 | 0.76 | HPGD (0.42) | RAB9ANPC1AVPR1AALDH1A1LMNA | |
| SCHEMBL18912121 | 0.76 | HSD11B1 (0.59) | ALDH1A1LMNAKMT2ATSHRHTT | |
| SCHEMBL889637 | 0.75 | HSD11B1 (0.56) | AVPR1AKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892618-A1 | 4-PYRIDINYL FORMAMIDE COMPOUND OR DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | Qingdao KingAgroot Chemical Compound Co., Ltd. (CN) | 2021-10-13 | — | — | EP | disclosed |