Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | OXTR | P30559 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22494221 | 0.87 | RAB9A (0.62) | RAB9ANPC1MAPTALDH1A1OXTR | |
| SCHEMBL23914162 | 0.81 | OXTR (0.55) | RAB9ANPC1MAPTALDH1A1OXTR | |
| SCHEMBL1544604 | 0.81 | NPC1 (0.51) | RAB9ANPC1MAPTALDH1A1LMNA | |
| SCHEMBL13828022 | 0.81 | MAPT (0.52) | RAB9ANPC1MAPTALDH1A1OXTR | |
| SCHEMBL12894618 | 0.80 | HPGD (0.39) | RAB9ANPC1MAPTALDH1A1LMNA | |
| SCHEMBL1544009 | 0.80 | TP53 (0.52) | RAB9ANPC1MAPTLMNAKMT2A | |
| SCHEMBL10012186 | 0.79 | OXTR (0.61) | RAB9AALDH1A1OXTRTDP1GLA | |
| SCHEMBL11511994 | 0.79 | ALDH1A1 (0.53) | RAB9ANPC1MAPTALDH1A1OXTR | |
| SCHEMBL1543958 | 0.78 | ALDH1A1 (0.52) | RAB9ANPC1ALDH1A1OXTRTDP1 | |
| SCHEMBL4184528 | 0.78 | HSD11B1 (0.43) | RAB9ANPC1MAPTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2259141-B1 | PROCESS FOR PRODUCING LITHOGRAPHIC PRINTING PLATE | FUJIFILM CORP (JP) | 2016-11-23 | — | — | EP | disclosed |
| EP-2157478-B1 | Method of producing lithographic printing plate | FUJIFILM CORP (JP) | 2013-05-29 | — | — | EP | disclosed |
| EP-1906245-B1 | Photopolymerization type photosensitive lithographic printing plate precursor | FUJIFILM CORP (JP) | 2013-02-27 | — | — | EP | disclosed |
| EP-1762894-B1 | Photopolymerizable photosensitive lithographic printing plate | FUJIFILM CORP (JP) | 2013-01-09 | — | — | EP | disclosed |
| US-20120295204-A1 | PROCESSING METHOD OF LITHOGRAPHIC PRINTING PLATE PREURSOR | FUJIFILM CORPORATION (JP) | 2012-11-22 | — | — | US | disclosed |
| US-20120295204-A1 | PROCESSING METHOD OF LITHOGRAPHIC PRINTING PLATE PREURSOR | FUJIFILM CORPORATION (JP) | 2012-11-22 | — | — | US | disclosed |
| US-8257913-B2 | Processing method of lithographic printing plate precursor | FUJIFILM CORPORATION (JP) | 2012-09-04 | — | — | US | disclosed |
| US-8257913-B2 | Processing method of lithographic printing plate precursor | FUJIFILM CORPORATION (JP) | 2012-09-04 | — | — | US | disclosed |
| US-8168370-B2 | Photosensitive composition which included photopolymerization initiator; graft polymer binder | FUJIFILM CORPORATION (JP) | 2012-05-01 | — | — | US | disclosed |
| US-8168370-B2 | Photosensitive composition which included photopolymerization initiator; graft polymer binder | FUJIFILM CORPORATION (JP) | 2012-05-01 | — | — | US | disclosed |
| US-20070128550-A1 | Method for preparation of lithographic printing plate and lithographic printing plate precursor | FUJIFILM CORPORATION (JP) | 2007-06-07 | — | — | US | disclosed |
| US-20070128550-A1 | Method for preparation of lithographic printing plate and lithographic printing plate precursor | FUJIFILM CORPORATION (JP) | 2007-06-07 | — | — | US | disclosed |
| EP-1762894-A1 | Photopolymerizable photosensitive lithographic printing plate | FUJIFILM Corporation (JP) | 2007-03-14 | — | — | EP | disclosed |
| US-20070048663-A1 | Photopolymerizable photosensitive lithographic printing plate | FUJI PHOTO FILM CO., LTD. | 2007-03-01 | — | — | US | disclosed |
| US-20070048663-A1 | Photopolymerizable photosensitive lithographic printing plate | FUJI PHOTO FILM CO., LTD. | 2007-03-01 | — | — | US | disclosed |
| US-20070020563-A1 | Method for preparation of lithographic printing plate and lithographic printing plate precursor | FUJI PHOTO FILM CO., LTD. | 2007-01-25 | — | — | US | disclosed |
| US-20070020563-A1 | Method for preparation of lithographic printing plate and lithographic printing plate precursor | FUJI PHOTO FILM CO., LTD. | 2007-01-25 | — | — | US | disclosed |
| US-20060122397-A1 | Exhibiting an activity at metabotropic glutamate receptors (mGluRs), especially at the mGluR5 receptor; neurological disorders, psychiatric disorders, acute and chronic pain | ASTRAZENECA AB (SE) | 2006-06-08 | — | — | US | disclosed |
| US-20050272779-A1 | Additional heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists | ASTRAZENECA AB | 2005-12-08 | — | — | US | disclosed |
| US-20040152699-A1 | Compounds | ASTRAZENECA AND NPS PHARMACEUTICALS, INC. | 2004-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152699-A1 | Compounds | SDHA, CYP11B2, CYP11B1 | RAB9A 1283/4885NPC1 6/4885MAPT 1620/4885 |
| US-20060122397-A1 | Exhibiting an activity at metabotropic glutamate receptors (mGluRs), especially at the mGluR5 receptor; neurological disorders, psychiatric disorders, acute and chronic pain | GRM5, GRIK5, GRM1 | RAB9A 1153/4885NPC1 1374/4885MAPT 1167/4885 |
| US-20050272779-A1 | Additional heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists | GRM5, GRIK5, GRM2 | RAB9A 1926/4885NPC1 554/4885MAPT 780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.