SCHEMBL23916505

SCHEMBL23916505

Nc1ccc(-c2ccc(C(F)F)nc2)c(-c2nnn[nH]2)c1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FEN1 P39748 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23916021 0.83 AAK1 (0.33)
SCHEMBL23916420 0.81 HPGDS (0.36)
SCHEMBL21135415 0.81 KCNH2 (0.41)
SCHEMBL23915977 0.79 KCNH2 (0.35)
SCHEMBL23915989 0.78 PDE3B (0.31) FEN1
SCHEMBL20329236 0.78 KCNH2 (0.41)
SCHEMBL23910009 0.78 MAP3K11 (0.41)
SCHEMBL21071491 0.78 PDE10A (0.42) FEN1
SCHEMBL23916453 0.78 GLA (0.34) FEN1
SCHEMBL14217428 0.77 ALDH1A1 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210317092-A1 TETRAZOLE CONTAINING COMPOUNDS BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2021-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210317092-A1 TETRAZOLE CONTAINING COMPOUNDS TSLP, IL5, TRPA1 FEN1 4761/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.