Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | HTT | P42858 | 2/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | NUDT14 | O95848 | 1/20 | 0.66 |
| ▸ | NUDT5 | Q9UKK9 | 1/20 | 0.66 |
| ▸ | PIK3CD | O00329 | 13/20 | 0.64 |
| ▸ | PIK3CA | P42336 | 13/20 | 0.64 |
| ▸ | PIK3CB | P42338 | 13/20 | 0.64 |
| ▸ | PIK3CG | P48736 | 13/20 | 0.64 |
| ▸ | PRKDC | P78527 | 13/20 | 0.64 |
| ▸ | SRC | P12931 | 13/20 | 0.64 |
| ▸ | ABL1 | P00519 | 12/20 | 0.64 |
| ▸ | EGFR | P00533 | 12/20 | 0.64 |
| ▸ | MTOR | P42345 | 11/20 | 0.64 |
| ▸ | HCK | P08631 | 11/20 | 0.64 |
| ▸ | KDR | P35968 | 11/20 | 0.64 |
| ▸ | EPHB4 | P54760 | 10/20 | 0.64 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30782445 | 0.88 | NUDT14 (0.69) | KDM4EALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL12366 | 0.88 | NUDT14 (0.69) | KDM4EALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL13826003 | 0.87 | SRC (0.68) | KDM4EALDH1A1LMNAHTTNUDT14 | |
| SCHEMBL13019672 | 0.85 | SRC (0.69) | SMN1; SMN2NUDT14NUDT5PIK3CDPIK3CA | |
| SCHEMBL21079131 | 0.85 | NUDT14 (0.66) | KDM4EALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL16886112 | 0.85 | PIK3CD (0.68) | KDM4EALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL130419 | 0.85 | PIK3CD (0.70) | KDM4EALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL409367 | 0.85 | PIK3CD (0.82) | NUDT14NUDT5PIK3CDPIK3CAPIK3CB | |
| SCHEMBL128512 | 0.85 | PIK3CD (0.60) | KDM4EALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL23917506 | 0.84 | NUDT14 (0.64) | KDM4EALDH1A1LMNAHTTNUDT14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4719385-A2 | 1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINES AS ANTI-INFECTIOUS AGENTS | University of Vermont and State Agricultural College (US) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024249380-A2 | 1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINES AS ANTI-INFECTIOUS AGENTS | UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) | 2024-12-05 | — | — | WO | disclosed |
| US-20210317140-A1 | Heterocyclic Compounds and Methods of Use | MEDIVATION TECHNOLOGIES, INC. (US) | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317140-A1 | Heterocyclic Compounds and Methods of Use | BTK, PIK3CD, PIK3CB | KDM4E 1755/4885ALDH1A1 4290/4885LMNA 3360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.