Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT14 | O95848 | 1/20 | 0.69 |
| ▸ | NUDT5 | Q9UKK9 | 1/20 | 0.69 |
| ▸ | PIK3CD | O00329 | 13/20 | 0.67 |
| ▸ | PIK3CA | P42336 | 13/20 | 0.67 |
| ▸ | PIK3CB | P42338 | 13/20 | 0.67 |
| ▸ | PIK3CG | P48736 | 13/20 | 0.67 |
| ▸ | PRKDC | P78527 | 13/20 | 0.67 |
| ▸ | ABL1 | P00519 | 13/20 | 0.67 |
| ▸ | SRC | P12931 | 13/20 | 0.67 |
| ▸ | EGFR | P00533 | 12/20 | 0.67 |
| ▸ | MTOR | P42345 | 11/20 | 0.67 |
| ▸ | HCK | P08631 | 11/20 | 0.67 |
| ▸ | KDR | P35968 | 11/20 | 0.67 |
| ▸ | EPHB4 | P54760 | 10/20 | 0.67 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.65 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.55 |
| ▸ | AURKA | O14965 | 1/20 | 0.55 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12366 | 1.00 | NUDT14 (0.69) | NUDT14NUDT5PIK3CDPIK3CAPIK3CB | |
| SCHEMBL13826003 | 0.89 | SRC (0.68) | NUDT14NUDT5PIK3CDPIK3CAPIK3CB | |
| SCHEMBL16886112 | 0.88 | PIK3CD (0.68) | NUDT14NUDT5PIK3CDPIK3CAPIK3CB | |
| SCHEMBL13019672 | 0.88 | SRC (0.69) | NUDT14NUDT5PIK3CDPIK3CAPIK3CB | |
| SCHEMBL21079131 | 0.88 | NUDT14 (0.66) | NUDT14NUDT5PIK3CDPIK3CAPIK3CB | |
| SCHEMBL23917243 | 0.88 | KDM4E (0.69) | NUDT14NUDT5PIK3CDPIK3CAPIK3CB | |
| SCHEMBL130419 | 0.88 | PIK3CD (0.70) | NUDT14NUDT5PIK3CDPIK3CAPIK3CB | |
| SCHEMBL409367 | 0.88 | PIK3CD (0.82) | NUDT14NUDT5PIK3CDPIK3CAPIK3CB | |
| SCHEMBL23917506 | 0.86 | NUDT14 (0.64) | NUDT14NUDT5PIK3CDPIK3CAPIK3CB | |
| SCHEMBL13826048 | 0.85 | NUDT14 (0.63) | NUDT14NUDT5PIK3CDPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112236429-B | Heteroaryl compounds useful as type II IRAK inhibitors and uses thereof | 默克专利有限公司 | 2024-10-11 | — | — | CN | disclosed |
| CN-117561260-A | Heterocyclic compound, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2024-02-13 | — | — | CN | disclosed |