Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT14 | O95848 | 1/20 | 0.64 |
| ▸ | NUDT5 | Q9UKK9 | 1/20 | 0.64 |
| ▸ | PIK3CD | O00329 | 12/20 | 0.63 |
| ▸ | PIK3CA | P42336 | 12/20 | 0.63 |
| ▸ | PIK3CB | P42338 | 12/20 | 0.63 |
| ▸ | PIK3CG | P48736 | 12/20 | 0.63 |
| ▸ | PRKDC | P78527 | 12/20 | 0.63 |
| ▸ | SRC | P12931 | 13/20 | 0.61 |
| ▸ | ABL1 | P00519 | 11/20 | 0.61 |
| ▸ | EGFR | P00533 | 11/20 | 0.61 |
| ▸ | MTOR | P42345 | 10/20 | 0.61 |
| ▸ | HCK | P08631 | 9/20 | 0.61 |
| ▸ | EPHB4 | P54760 | 9/20 | 0.61 |
| ▸ | KDR | P35968 | 9/20 | 0.61 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.60 |
| ▸ | RET | P07949 | 3/20 | 0.52 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.51 |
| ▸ | AURKA | O14965 | 1/20 | 0.51 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL409367 | 0.86 | PIK3CD (0.82) | NUDT14NUDT5PIK3CDPIK3CAPIK3CB | |
| SCHEMBL12366 | 0.86 | NUDT14 (0.69) | NUDT14NUDT5PIK3CDPIK3CAPIK3CB | |
| SCHEMBL30782445 | 0.86 | NUDT14 (0.69) | NUDT14NUDT5PIK3CDPIK3CAPIK3CB | |
| SCHEMBL13826003 | 0.85 | SRC (0.68) | NUDT14NUDT5PIK3CDPIK3CAPIK3CB | |
| SCHEMBL16886112 | 0.84 | PIK3CD (0.68) | NUDT14NUDT5PIK3CDPIK3CAPIK3CB | |
| SCHEMBL13019672 | 0.84 | SRC (0.69) | NUDT14NUDT5PIK3CDPIK3CAPIK3CB | |
| SCHEMBL23917243 | 0.84 | KDM4E (0.69) | NUDT14NUDT5PIK3CDPIK3CAPIK3CB | |
| SCHEMBL130419 | 0.84 | PIK3CD (0.70) | NUDT14NUDT5PIK3CDPIK3CAPIK3CB | |
| SCHEMBL21079131 | 0.84 | NUDT14 (0.66) | NUDT14NUDT5PIK3CDPIK3CAPIK3CB | |
| SCHEMBL130618 | 0.83 | PIK3CD (0.68) | NUDT14NUDT5PIK3CDPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317140-A1 | Heterocyclic Compounds and Methods of Use | MEDIVATION TECHNOLOGIES, INC. (US) | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317140-A1 | Heterocyclic Compounds and Methods of Use | BTK, PIK3CD, PIK3CB | NUDT14 1479/4885NUDT5 1329/4885PIK3CD 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.