Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | BCHE | P06276 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4318567 | 0.83 | FPR2 (0.54) | FPR2POLBBCHEALOX15PTGS2 | |
| SCHEMBL4321221 | 0.79 | BCHE (0.45) | FPR2POLBGAABCHEALOX15 | |
| SCHEMBL4319898 | 0.77 | BCHE (0.43) | FPR2POLBGAABCHEALOX15 | |
| SCHEMBL29993 | 0.72 | ALDH1A1 (0.64) | POLBGAABCHEALOX15PTGS2 | |
| SCHEMBL4320070 | 0.71 | ALDH1A1 (0.56) | POLBGAAALDH1A1SMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL28445202 | 0.70 | ALDH1A1 (0.62) | FPR2POLBGAABCHEALOX15 | |
| SCHEMBL9809088 | 0.70 | FPR2 (0.47) | FPR2POLBGAABCHEALOX15 | |
| SCHEMBL4332839 | 0.70 | HTR1A (0.55) | GAAALDH1A1 | |
| SCHEMBL4332295 | 0.69 | SMN1; SMN2 (0.53) | BCHEALDH1A1SMN1; SMN2 | |
| SCHEMBL8259595 | 0.69 | FPR2 (0.41) | FPR2GAAALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892734-A1 | SCREENING METHODS AND THERAPEUTIC APPLICATIONS BASED ON BACTERIAL MOTILITY INHIBITION | Ludwig-Maximilians-Universität München (DE) | 2021-10-13 | — | — | EP | disclosed |