SCHEMBL29993

SCHEMBL29993

Cc1c(Cl)c(=O)n(-c2ccccc2)n1C

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.64
ALOX15 P16050 2/20 0.64
BCHE P06276 2/20 0.64
PTGS2 P35354 1/20 0.64
LMNA P02545 2/20 0.62
ADORA3 P0DMS8 1/20 0.62
TSHR P16473 4/20 0.60
CYP1A2 P05177 2/20 0.60
THRB P10828 1/20 0.60
NAPRT Q6XQN6 1/20 0.60
KMT2A Q03164 3/20 0.57
KDM4E B2RXH2 2/20 0.55
CYP2D6 P10635 1/20 0.55
MEN1 O00255 2/20 0.55
POLB P06746 1/20 0.54
GAA P10253 2/20 0.54
CYP19A1 P11511 1/20 0.54
MAPT P10636 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28445202 0.98 ALDH1A1 (0.62) ALDH1A1ALOX15BCHEPTGS2LMNA
SCHEMBL8258700 0.85 TSHR (0.48) ALDH1A1ALOX15BCHEPTGS2LMNA
SCHEMBL4320077 0.85 GAA (0.50) ALDH1A1ALOX15BCHEPTGS2LMNA
SCHEMBL4318702 0.82 KMT2A (0.51) ALDH1A1ALOX15BCHEPTGS2LMNA
SCHEMBL588715 0.81 ALDH1A1 (0.68) ALDH1A1ALOX15BCHEPTGS2LMNA
SCHEMBL2449608 0.81 ALOX15 (0.68) ALDH1A1ALOX15BCHEPTGS2LMNA
SCHEMBL11313942 0.80 LMNA (0.81) ALDH1A1BCHEPTGS2LMNAADORA3
Hydrochloric Acid SCHEMBL28311112 0.79 ALOX15 (0.66) ALDH1A1ALOX15BCHEPTGS2LMNA
SCHEMBL27660283 0.79 ALOX15 (0.66) ALDH1A1ALOX15BCHEPTGS2LMNA
SCHEMBL4321369 0.78 FPR2 (0.49) ALDH1A1ALOX15BCHEPTGS2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 362 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118026938-B Pyrazolone ester compound and electrochemical synthesis method thereof 江西本草天工科技有限责任公司 2024-06-28 CN claimed
CN-118026938-A Pyrazolone ester compound and electrochemical synthesis method thereof 江西本草天工科技有限责任公司 2024-05-14 CN claimed
US-9770514-B2 Tamper-resistant pharmaceutical dosage forms ExxPharma Therapeutics LLC (US) 2017-09-26 US claimed
CN-104825397-A Controlled release delivery device containing organosol coating ISA ODIDI 2015-08-12 CN claimed
US-20150064250-A1 Tamper-Resistant Pharmaceutical Dosage Forms ExxPharma Therapeutics LLC (US) 2015-03-05 US claimed
CN-102014625-A Novel formulations for the treatment of migraine ZOGENIX INC 2011-04-13 CN claimed
EP-4168092-B1 BALLOON CATHETER WITH PRECISION DRUG-ELUTING CAPABILITY BARD INC C R (US) 2026-05-27 EP disclosed
US-20260097102-A1 Treatment Of Respiratory Disorders With Arachidonate 15-Lipoxygenase (ALOX15) Inhibitors REGENERON PHARMA (US) 2026-04-09 US disclosed
US-12472241-B2 Treatment of respiratory disorders with arachidonate 15-lipoxygenase (ALOX15) inhibitors REGENERON PHARMACEUTICALS, INC. (US) 2025-11-18 US disclosed
US-12458392-B2 Scoring balloon with translating scoring wires C.R. BARD, INC. (US) 2025-11-04 US disclosed
US-12167883-B2 Medical device including expandable muscle polymer BARD PERIPHERAL VASCULAR, INC. (US) 2024-12-17 US disclosed
CN-118026938-B Pyrazolone ester compound and electrochemical synthesis method thereof 江西本草天工科技有限责任公司 2024-06-28 CN disclosed
CN-118026938-A Pyrazolone ester compound and electrochemical synthesis method thereof 江西本草天工科技有限责任公司 2024-05-14 CN disclosed
WO-2004011055-A2 IMPLANTABLE OR INSERTABLE MEDICAL DEVICES FOR CONTROLLED DRUG DELIVERY SCIMED LIFE SYSTEMS, INC. (US) 2004-02-05 WO disclosed
US-20030224033-A1 Implantable or insertable medical devices for controlled drug delivery BOSTON SCIENTIFIC SCIMED, INC. 2003-12-04 US disclosed
CN-1122719-C Modified biological material IMUTRAN LTD (GB) 2003-10-01 CN disclosed
CN-1148891-A Method of quantifying cholesterol in low-density of very-low-density lipoprotein KYOWA MEDEX CO LTD (JP) 1997-04-30 CN disclosed
CN-1051199-A MODIFIED BIOLOGICAL MATERIAL IMUTRAN LTD (GB) 1991-05-08 CN disclosed
US-4499104-A ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC, ANTICONVULSANT AGENTS FARMATIS S.R.L. (IT) 1985-02-12 US disclosed
US-4115096-A Dihydropyrazolone herbicide FMC CORPORATION (US) 1978-09-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260097102-A1 Treatment Of Respiratory Disorders With Arachidonate 15-Lipoxygenase (ALOX15) Inhibitors ALOX15, ALOX15B, ALOX5 ALDH1A1 900/4885ALOX15 1/4885BCHE 4667/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.