Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 2/20 | 0.33 |
| ▸ | CASP7 | P55210 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.33 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23919130 | 0.89 | MAPT (0.36) | POLBMEN1KMT2AHTR7L3MBTL1 | |
| SCHEMBL23919144 | 0.86 | KDM4E (0.35) | POLBMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL22145125 | 0.84 | PPARG (0.33) | POLBMEN1KMT2AUSP2CYP1A2 | |
| SCHEMBL22145201 | 0.81 | MAPT (0.36) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL22145212 | 0.81 | — | — | |
| SCHEMBL23919146 | 0.81 | MAPT (0.34) | POLBMEN1KMT2AL3MBTL1USP2 | |
| SCHEMBL26937413 | 0.80 | MAPT (0.38) | MEN1KMT2AL3MBTL1ALDH1A1PIK3CA | |
| SCHEMBL22145129 | 0.80 | LMNA (0.36) | MEN1KMT2AL3MBTL1USP2ALDH1A1 | |
| SCHEMBL22145135 | 0.79 | EDNRA (0.36) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL22145205 | 0.79 | EDNRA (0.34) | MEN1KMT2AL3MBTL1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317129-A1 | Indolenaphthopyrans | TRANSITIONS OPTICAL, LTD. (IE) | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317129-A1 | Indolenaphthopyrans | AHR, TDO2, TPH2 | POLB 2726/4885MEN1 3107/4885KMT2A 2760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.