Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | EDNRA | P25101 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 4/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23919130 | 0.97 | MAPT (0.36) | KDM4EMAPTNPSR1EDNRAALDH1A1 | |
| SCHEMBL22145205 | 0.91 | EDNRA (0.34) | KDM4EMAPTEDNRAALDH1A1SMN1; SMN2 | |
| SCHEMBL22145250 | 0.91 | KDM4E (0.36) | KDM4EMAPTEDNRAALDH1A1SMN1; SMN2 | |
| SCHEMBL22145201 | 0.88 | MAPT (0.36) | KDM4EMAPTEDNRAALDH1A1SMN1; SMN2 | |
| SCHEMBL22145135 | 0.88 | EDNRA (0.36) | KDM4EMAPTNPSR1EDNRAALDH1A1 | |
| SCHEMBL22145217 | 0.87 | MAT2A (0.39) | ALDH1A1POLBPPARG | |
| SCHEMBL22145207 | 0.87 | KDM4E (0.33) | KDM4EMAPTEDNRAALDH1A1SMN1; SMN2 | |
| SCHEMBL23919153 | 0.86 | POLB (0.36) | KDM4EMAPTNPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL22145210 | 0.84 | ALDH1A1 (0.31) | KDM4EMAPTEDNRAALDH1A1TP53 | |
| SCHEMBL22145208 | 0.84 | SMN1; SMN2 (0.35) | KDM4EMAPTEDNRAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317129-A1 | Indolenaphthopyrans | TRANSITIONS OPTICAL, LTD. (IE) | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317129-A1 | Indolenaphthopyrans | AHR, TDO2, TPH2 | KDM4E 3276/4885MAPT 3512/4885NPSR1 54/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.