SCHEMBL23919941

SCHEMBL23919941

Cc1c(C(c2ccccc2)c2ccc(O)c(O)c2C)ccc(O)c1O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 2/20 0.41
HKDC1 Q2TB90 1/20 0.37
GAA P10253 4/20 0.36
HPGD P15428 2/20 0.36
MAPT P10636 2/20 0.36
ALDH1A1 P00352 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
KDM4E B2RXH2 1/20 0.36
USP2 O75604 1/20 0.36
POLB P06746 1/20 0.36
ALOX15 P16050 1/20 0.36
ALOX12 P18054 1/20 0.36
RECQL P46063 1/20 0.36
HSD17B10 Q99714 1/20 0.36
TSHR P16473 1/20 0.35
SLC6A4 P31645 2/20 0.35
LMNA P02545 1/20 0.35
ESR1 P03372 1/20 0.35
CHRM2 P08172 1/20 0.35
CHRM4 P08173 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7773962 0.82 TYR (0.40) TYRHKDC1GAAHPGDMAPT
SCHEMBL6744407 0.78 TYR (0.40) TYRHKDC1GAAHPGDMAPT
SCHEMBL19806914 0.74 HPGD (0.46) TYRHKDC1GAAHPGDMAPT
SCHEMBL50970 0.73 TRPA1 (0.57) TYRGAAHPGDMAPTALDH1A1
SCHEMBL51095 0.73 CHRM1 (0.55) TYRGAAHPGDMAPTALDH1A1
SCHEMBL15011592 0.73 LMNA (0.50) TYRHPGDTSHRLMNACHRM1
SCHEMBL1176905 0.72 GAA (0.40) TYRHKDC1GAAHPGDMAPT
SCHEMBL30485783 0.72 GAA (0.40) TYRHKDC1GAAHPGDMAPT
SCHEMBL1345518 0.72 CHRM1 (0.50) TYRGAAHPGDMAPTALDH1A1
SCHEMBL1345618 0.72 CHRM1 (0.50) TYRGAAHPGDMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11572442-B2 Compound, polyimide resin and method of producing the same, photosensitive resin composition, patterning method and method of forming cured film, interlayer insulating film, surface protective film, and electronic component INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2023-02-07 US disclosed
US-20210317270-A1 NOVEL COMPOUND, POLYIMIDE RESIN AND METHOD OF PRODUCING THE SAME, PHOTOSENSITIVE RESIN COMPOSITION, PATTERNING METHOD AND METHOD OF FORMING CURED FILM, INTERLAYER INSULATING FILM, SURFACE PROTECTIVE FILM, AND ELECTRONIC COMPONENT SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11572442-B2 Compound, polyimide resin and method of producing the same, photosensitive resin composition, patterning method and method of forming cured film, interlayer insulating film, surface protective film, and electronic component BRIX1, RBX1, HAX1 TYR 1809/4885HKDC1 4076/4885GAA 3990/4885
US-20210317270-A1 NOVEL COMPOUND, POLYIMIDE RESIN AND METHOD OF PRODUCING THE SAME, PHOTOSENSITIVE RESIN COMPOSITION, PATTERNING METHOD AND METHOD OF FORMING CURED FILM, INTERLAYER INSULATING FILM, SURFACE PROTECTIVE FILM, AND ELECTRONIC COMPONENT BRIX1, HAX1, RBX1 TYR 1727/4885HKDC1 3816/4885GAA 3869/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.