Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | LYN | P07948 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.32 |
| ▸ | SIK1 | P57059 | 1/20 | 0.32 |
| ▸ | SIK2 | Q9H0K1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22206967 | 0.88 | GRM2 (0.38) | HPGDKDM4EALDH1A1L3MBTL1GRM2 | |
| SCHEMBL22206966 | 0.88 | GRM2 (0.38) | HPGDKDM4EALDH1A1L3MBTL1GRM2 | |
| SCHEMBL22216432 | 0.85 | KDM4E (0.38) | HPGDKDM4EALDH1A1L3MBTL1GRM2 | |
| SCHEMBL22216433 | 0.85 | L3MBTL1 (0.56) | L3MBTL1ACHELMNAMAPTCYP2C19 | |
| SCHEMBL22216435 | 0.84 | L3MBTL1 (0.39) | HPGDKDM4EALDH1A1L3MBTL1ACHE | |
| SCHEMBL22216455 | 0.83 | LMNA (0.42) | HPGDKDM4EALDH1A1L3MBTL1ACHE | |
| SCHEMBL22216190 | 0.82 | AOC3 (0.42) | HPGDKDM4EALDH1A1L3MBTL1ACHE | |
| SCHEMBL22216353 | 0.80 | POLB (0.51) | HPGDKDM4EALDH1A1MAPTCYP2C19 | |
| SCHEMBL28427420 | 0.80 | HDAC3 (0.33) | HPGDKDM4EALDH1A1GRM2ACHE | |
| SCHEMBL28427418 | 0.80 | HDAC3 (0.33) | HPGDKDM4EALDH1A1GRM2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892621-A1 | HALOALLYLAMINE COMPOUNDS AND APPLICATION THEREOF | Nanjing Transthera Biosciences Co., Ltd. (CN) | 2021-10-13 | — | — | EP | disclosed |