Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | KDM4B | O94953 | 1/20 | 0.38 |
| ▸ | KDM5C | P41229 | 1/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.38 |
| ▸ | HPRT1 | P00492 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 3/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | PNP | P00491 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20224894 | 0.83 | ADORA2A (0.46) | HPRT1ALDH1A1PDE4APDE4BPDE4C | |
| SCHEMBL21127684 | 0.80 | HPRT1 (0.40) | HPRT1ALDH1A1CYP1A2KMT2APNP | |
| SCHEMBL21504444 | 0.75 | PNP (0.54) | KMT2APNP | |
| SCHEMBL9476371 | 0.72 | LMNA (0.53) | ALDH1A1KMT2AADORA2A | |
| SCHEMBL9477367 | 0.71 | ADORA3 (0.46) | ALDH1A1KMT2AADORA2AMAPT | |
| SCHEMBL24434393 | 0.70 | HPRT1 (0.40) | HPRT1ALDH1A1KMT2APNP | |
| SCHEMBL21637052 | 0.70 | ALDH1A1 (0.39) | HPRT1ALDH1A1PDE4APDE4BPDE4C | |
| SCHEMBL24499073 | 0.70 | ALDH1A1 (0.39) | HPRT1ALDH1A1PDPK1PNP | |
| SCHEMBL9476624 | 0.70 | TSHR (0.61) | ALDH1A1KMT2AADORA2AMAPT | |
| SCHEMBL9476477 | 0.70 | MEN1 (0.62) | ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11149052-B2 | 2′3′-cyclic dinucleotides | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. (CZ) | 2021-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11149052-B2 | 2′3′-cyclic dinucleotides | STING1, MAVS, CGAS | KDM4A 2951/4885KDM4B 3467/4885KDM5C 3331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.