SCHEMBL23922673

SCHEMBL23922673

CCC(C)(C)OOC(=O)c1cccc(C(=O)c2cccc(C(=O)OOC(C)(C)CC)c2C(=O)OOC(C)(C)CC)c1C(=O)OOC(C)(C)CC

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.37
TSHR P16473 5/20 0.36
ALDH1A1 P00352 4/20 0.36
TDP1 Q9NUW8 3/20 0.36
HSD17B10 Q99714 2/20 0.36
CDC25B P30305 1/20 0.35
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
CA14 Q9ULX7 1/20 0.33
L3MBTL1 Q9Y468 2/20 0.32
TP53 P04637 1/20 0.31
CYP3A4 P08684 1/20 0.31
MAPK1 P28482 1/20 0.31
CLEC4M Q9H2X3 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
KMT2A Q03164 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23922685 0.87 TSHR (0.35) ELANETSHRALDH1A1TDP1HSD17B10
SCHEMBL2872626 0.84 TSHR (0.51) ELANETSHRALDH1A1TDP1HSD17B10
SCHEMBL2030231 0.84 TSHR (0.50) ELANETSHRALDH1A1TDP1HSD17B10
SCHEMBL27458878 0.78 ALDH1A1 (0.41) ELANETSHRALDH1A1TDP1HSD17B10
SCHEMBL22773852 0.78 ADRB2 (0.45) TSHRALDH1A1TDP1HSD17B10L3MBTL1
SCHEMBL6162550 0.78 TSHR (0.44) ELANETSHRALDH1A1TDP1HSD17B10
SCHEMBL4612232 0.78 ELANE (0.49) ELANETSHRALDH1A1TDP1HSD17B10
SCHEMBL10437438 0.78 MAPK1 (0.46) ELANETSHRALDH1A1TDP1HSD17B10
SCHEMBL9103099 0.77 TSHR (0.43) ELANETSHRALDH1A1TDP1HSD17B10
SCHEMBL27927289 0.77 ALDH1A1 (0.57) TSHRALDH1A1TDP1HSD17B10CDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3182204-B1 PLANOGRAPHIC PRINTING PLATE PRECURSOR USING A POLYMERIZABLE COMPOSITION FUJIFILM CORP (JP) 2021-10-20 EP disclosed