Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | WRN | Q14191 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | DGKA | P23743 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21352287 | 0.86 | DGKA (0.42) | ALOX12GAASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL27664746 | 0.85 | ALOX12 (0.45) | ALOX12SMN1; SMN2ALDH1A1HPGDBLM | |
| SCHEMBL8744647 | 0.82 | ALOX12 (0.46) | ALOX12SMN1; SMN2ALDH1A1HPGDKDM4E | |
| SCHEMBL28236067 | 0.81 | ALOX12 (0.41) | ALOX12GAASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL20786977 | 0.81 | ALOX12 (0.43) | ALOX12SMN1; SMN2HPGDKDM4EPOLB | |
| SCHEMBL13540116 | 0.79 | GAA (0.41) | ALOX12GAASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL28145893 | 0.78 | KDM4E (0.37) | ALOX12SMN1; SMN2ALDH1A1HPGDKDM4E | |
| SCHEMBL9329901 | 0.78 | DGKA (0.37) | GAAALDH1A1HPGDCYP1A2CYP2C19 | |
| SCHEMBL16290005 | 0.78 | ALOX12 (0.53) | ALOX12GAASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL4702471 | 0.77 | NAAA (0.47) | ALOX12GAAALDH1A1HPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110201234-A | A kind of used in tissue engineering prostatic cell micro-capsule and preparation method thereof | 山东百多安医疗器械有限公司 | 2019-09-06 | — | — | CN | claimed |
| CN-109893657-B | Gene delivery carrier, drug compound, anti-pulmonary fibrosis drug and application | 中国人民解放军军事科学院军事医学研究院 | 2022-04-29 | — | — | CN | disclosed |
| US-20220125939-A1 | METHOD OF PREPARING PEGYLATED BIOMOLECULES HAVING CONTROLLABLE BINDING SITES | JENKEM TECHNOLOGY CO., LTD. (TIANJIN) (CN) | 2022-04-28 | — | — | US | disclosed |
| EP-3896079-A1 | METHOD OF PREPARING PEGYLATED BIOMOLECULES HAVING CONTROLLABLE BINDING SITES | Jenkem Technology Co. Ltd. (Tianjin) (CN) | 2021-10-20 | — | — | EP | disclosed |
| CN-101357986-B | Polyethylene glycol functional derivative and preparation method thereof | BIO CANCER TREATMENT INT LTD | 2013-06-05 | — | — | CN | disclosed |
| CN-101357986-A | Polyethylene glycol functional derivative and preparation method thereof | KANGDA MEDICAL SCIENCE AND TEC (HK) | 2009-02-04 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220125939-A1 | METHOD OF PREPARING PEGYLATED BIOMOLECULES HAVING CONTROLLABLE BINDING SITES | IL2RA, IL2, HBG2 | ALOX12 3109/4885GAA 1565/4885SMN1; SMN2 4869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.