Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.39 |
| ▸ | ATF1 | P18846 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
| ▸ | AGER | Q15109 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1916945 | 0.80 | CYP3A4 (0.51) | ALDH1A1KDM4ECYP1A2TSHR | |
| SCHEMBL12067848 | 0.80 | ALDH1A1 (0.43) | ALDH1A1KDM4ESMN1; SMN2ATF1NFKB1 | |
| SCHEMBL14300707 | 0.80 | KMT2A (0.40) | ALDH1A1KDM4ESMN1; SMN2ATF1NFKB1 | |
| SCHEMBL29594643 | 0.79 | ALK (0.54) | EGFRKDRALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL28728853 | 0.79 | ALK (0.54) | EGFRKDRALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL858362 | 0.78 | KDM4E (0.35) | EGFRKDRALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL858364 | 0.78 | KDM4E (0.35) | EGFRKDRALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL14556227 | 0.78 | ALDH1A1 (0.49) | ALDH1A1KDM4ESMN1; SMN2CYP1A2 | |
| SCHEMBL23924890 | 0.77 | ALDH1A1 (0.38) | EGFRALDH1A1CYP1A2TSHRADORA3 | |
| SCHEMBL30462001 | 0.76 | ALDH1A1 (0.47) | EGFRKDRALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11970511-B2 | Tetrahydropyran-based thiodisaccharide mimics as Galectin-3 inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-04-30 | — | — | US | disclosed |
| EP-3807290-B1 | TETRAHYDROPYRAN-BASED THIODISACCHARIDE MIMICS AS GALECTIN-3 INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2022-03-30 | — | — | EP | disclosed |
| US-20210323991-A1 | TETRAHYDROPYRAN-BASED THIODISACCHARIDE MIMICS AS GALECTIN-3 INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2021-10-21 | — | — | US | disclosed |
| US-20210323991-A1 | TETRAHYDROPYRAN-BASED THIODISACCHARIDE MIMICS AS GALECTIN-3 INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2021-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11970511-B2 | Tetrahydropyran-based thiodisaccharide mimics as Galectin-3 inhibitors | LGALS3, LGALS1, LGALS3BP | EGFR 2203/4885KDR 4010/4885ALDH1A1 2364/4885 |
| US-20210323991-A1 | TETRAHYDROPYRAN-BASED THIODISACCHARIDE MIMICS AS GALECTIN-3 INHIBITORS | LGALS3, LGALS1, LGALS3BP | EGFR 2203/4885KDR 4010/4885ALDH1A1 2364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.