Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL20604460 | 0.99 | POLB (0.34) | HTR1AHTR7KDM4ECHRM3CHRM2 | |
| SCHEMBL23926446 | 0.92 | CHRM3 (0.34) | HTR1AHTR7KDM4ECHRM3CYP2D6 | |
| Bromide SCHEMBL20604528 | 0.90 | CHRM3 (0.36) | HTR1AHTR7KDM4ECHRM3CHRM2 | |
| SCHEMBL23926424 | 0.76 | APP (0.37) | CHRM3CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL91232 | 0.75 | ALDH1A1 (0.50) | HTR7KDM4EPOLBLMNAJAK2 | |
| Bromide SCHEMBL20604553 | 0.75 | CHRNB2 (0.36) | CHRM3POLBL3MBTL1CHRNB2CHRNB4 | |
| SCHEMBL23926452 | 0.74 | HTR1A (0.36) | HTR1AHTR7CHRM3CYP2D6KMT2A | |
| SCHEMBL16560592 | 0.73 | LMNA (0.42) | KDM4EPOLBLMNAJAK2GAA | |
| Bromide SCHEMBL20604466 | 0.73 | HTR1A (0.35) | HTR1AHTR7CHRM3CHRM2CYP2D6 | |
| SCHEMBL16560595 | 0.72 | ALDH1A1 (0.42) | KDM4EPOLBL3MBTL1LMNAJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3423441-B1 | IODINATED ANALOGS OF CHOLINE, METHODS OF PREPARATION THEREOF, AND USE THEREOF AS MEDICAMENTS | UNIV PALACKEHO (CZ) | 2021-10-27 | — | — | EP | claimed |