Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.38 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28364530 | 0.85 | THRB (0.47) | LMNATSHRNFKB1PMP22CYP2D6 | |
| SCHEMBL2392881 | 0.84 | LMNA (0.44) | LMNATSHRNFKB1PMP22CYP2D6 | |
| SCHEMBL3213831 | 0.79 | ADRA1A (0.43) | LMNATSHRNFKB1PMP22CYP2D6 | |
| SCHEMBL8815905 | 0.76 | LMNA (0.39) | LMNATSHRNFKB1PMP22CYP2D6 | |
| SCHEMBL30166762 | 0.74 | GNPAT (0.38) | LMNATSHRNFKB1PMP22CYP2D6 | |
| SCHEMBL29290 | 0.74 | LMNA (0.52) | LMNATSHRNFKB1PMP22CYP2D6 | |
| SCHEMBL27739960 | 0.74 | LMNA (0.52) | LMNATSHRNFKB1PMP22CYP2D6 | |
| SCHEMBL29801908 | 0.73 | LMNA (0.58) | LMNATSHRNFKB1PMP22CYP2D6 | |
| SCHEMBL498122 | 0.72 | TSHR (0.55) | LMNATSHRNFKB1PMP22CYP2D6 | |
| SCHEMBL8232146 | 0.72 | TSHR (0.55) | LMNATSHRNFKB1PMP22CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9528114-B2 | Method for amplifying locus in bacterial cell | DANISCO US INC. (US) | 2016-12-27 | — | — | US | disclosed |
| EP-2257629-B1 | METHOD FOR AMPLIFYING LOCUS IN BACTERIAL CELL | DANISCO US INC (US) | 2016-03-16 | — | — | EP | disclosed |
| US-20110229938-A1 | Method For Amplifying Locus In Bacterial Cell | DANISCO US INC. | 2011-09-22 | — | — | US | disclosed |
| EP-2257629-A1 | METHOD FOR AMPLIFYING LOCUS IN BACTERIAL CELL | Danisco US Inc. (US) | 2010-12-08 | — | — | EP | disclosed |
| WO-2009120929-A1 | METHOD FOR AMPLIFYING LOCUS IN BACTERIAL CELL | DANISCO US INC., GENENCOR DIVISION (US) | 2009-10-01 | — | — | WO | disclosed |