Sugi Predict

Sugi Predict / Compounds / SCHEMBL3213831

SCHEMBL3213831

SCHEMBL3213831

CC(=O)NC(N)(CCCCC(=O)O)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ADRA1A P35348 1/20 0.43
▸ LMNA P02545 3/20 0.39
▸ ALDH1A1 P00352 4/20 0.39
▸ MEN1 O00255 3/20 0.39
▸ KMT2A Q03164 3/20 0.39
▸ THRB P10828 2/20 0.39
▸ CYP1A2 P05177 1/20 0.39
▸ TSHR P16473 5/20 0.38
▸ NFKB1 P19838 2/20 0.38
▸ PMP22 Q01453 1/20 0.38
▸ NAALAD2 Q9Y3Q0 1/20 0.38
▸ AKR1B1 P15121 1/20 0.38
▸ CYP2D6 P10635 1/20 0.38
▸ GPR84 Q9NQS5 6/20 0.36
▸ PPARG P37231 6/20 0.36
▸ PPARD Q03181 6/20 0.36
▸ PPARA Q07869 6/20 0.36
▸ HDAC11 Q96DB2 5/20 0.36
▸ TLR2 O60603 2/20 0.36
▸ TDP1 Q9NUW8 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30020404 0.82 THRB (0.35) MEN1KMT2ATHRB
SCHEMBL1373235 0.80 ALDH1A1 (0.36) LMNAALDH1A1MEN1KMT2ATHRB
SCHEMBL30019643 0.80 THRB (0.33) THRB
SCHEMBL28652757 0.80 THRB (0.33) THRB
SCHEMBL2392741 0.79 LMNA (0.44) LMNAALDH1A1MEN1KMT2ATHRB
SCHEMBL2392881 0.79 LMNA (0.44) LMNAALDH1A1MEN1KMT2ATHRB
SCHEMBL622765 0.76 GRM8 (0.42) LMNAALDH1A1CYP1A2NFKB1CYP2D6
SCHEMBL5964600 0.76 GRM8 (0.42) LMNAALDH1A1CYP1A2NFKB1CYP2D6
SCHEMBL3850920 0.76 GRM8 (0.42) LMNAALDH1A1CYP1A2NFKB1CYP2D6
SCHEMBL3987945 0.76 GRM8 (0.42) LMNAALDH1A1CYP1A2NFKB1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113817761-B Escherichia coli chassis bacteria without tricarboxylic acid cycle, construction method and application thereof 中国科学院微生物研究所 2023-08-11 — — CN disclosed
US-20220228154-A1 Methods for Screening Bacteria, Archaea, Algae, and Yeast Using CRISPR Nucleic Acids NORTH CAROLINA STATE UNIVERSITY 2022-07-21 — — US disclosed
US-11261451-B2 Methods for screening bacteria, archaea, algae, and yeast using CRISPR nucleic acids NORTH CAROLINA STATE UNIVERSITY (US) 2022-03-01 — — US disclosed
CN-113817761-A Escherichia coli chassis bacteria without tricarboxylic acid cycle and construction method and application thereof 中国科学院微生物研究所 2021-12-21 — — CN disclosed
US-10689638-B2 Thermophilic and thermoacidophilic metabolism genes and enzymes from Alicyclobacillus acidocaldarius and related organisms, methods UNITED STATES DEPARTMENT OF ENERGY 2020-06-23 — — US disclosed
US-20200095568-A1 Thermophilic and Thermoacidophilic Metabolism Genes and Enzymes from Alicyclobacillus Acidocaldarius and Related Organisms, Methods UNITED STATES DEPARTMENT OF ENERGY 2020-03-26 — — US disclosed
US-20190127723-A1 Thermophilic and Thermoacidophilic Metabolism Genes and Enzymes from Alicyclobacillus Acidocaldarius and Related Organisms, Methods UNITED STATES DEPARTMENT OF ENERGY 2019-05-02 — — US disclosed
US-20190021343-A1 METHODS FOR SCREENING BACTERIA, ARCHAEA, ALGAE, AND YEAST USING CRISPR NUCLEIC ACIDS UNIV NORTH CAROLINA STATE (US) 2019-01-24 — — US disclosed
US-10136649-B2 Methods for screening bacteria, archaea, algae, and yeast using CRISPR nucleic acids NORTH CAROLINA STATE UNIVERSITY (US) 2018-11-27 — — US disclosed
US-20180135037-A1 THERMOPHILIC AND THERMOACIDOPHILIC METABOLISM GENES AND ENZYMES FROM ALICYCLOBACILLUS ACIDOCALDARIUS AND RELATED ORGANISMS, METHODS UNITED STATES DEPARTMENT OF ENERGY 2018-05-17 — — US disclosed
US-20170051271-A1 THERMOPHILIC AND THERMOACIDOPHILIC METABOLISM GENES AND ENZYMES FROM ALICYCLOBACILLUS ACIDOCALDARIUS AND RELATED ORGANISMS, METHODS UNITED STATES DEPARTMENT OF ENERGY 2017-02-23 — — US disclosed
US-20160345578-A1 METHODS FOR SCREENING BACTERIA, ARCHAEA, ALGAE, AND YEAST USING CRISPR NUCLEIC ACIDS NORTH CAROLINA STATE UNIVERSITY 2016-12-01 — — US disclosed
US-20160046911-A1 THERMOPHILIC AND THERMOACIDOPHILIC METABOLISM GENES AND ENZYMES FROM ALICYCLOBACILLUS ACIDOCALDARIUS AND RELATED ORGANISMS, METHODS BATTELLE ENERGY ALLIANCE LLC (US) 2016-02-18 — — US disclosed
US-9222094-B2 Thermophilic and thermoacidophilic metabolism genes and enzymes from alicyclobacillus acidocaldarius and related organisms, methods BATTELLE ENERGY ALLIANCE, LLC (US) 2015-12-29 — — US disclosed
US-20140227788-A1 THERMOPHILIC AND THERMOACIDOPHILIC METABOLISM GENES AND ENZYMES FROM ALICYCLOBACILLUS ACIDOCALDARIUS AND RELATED ORGANISMS, METHODS BATTELLE ENERGY ALLIANCE, LLC (US) 2014-08-14 — — US disclosed
US-8728803-B2 Thermophilic and thermoacidophilic metabolism genes and enzymes from Alicyclobacillus acidocaldarius and related organisms, methods BATTELLE ENERGY ALLIANCE, LLC (US) 2014-05-20 — — US disclosed
EP-2245143-A2 THERMOPHILIC AND THERMOACIDOPHILIC METABOLISM GENES AND ENZYMES FROM ALICYCLOBACILLUS ACIDOCALDARIUS AND RELATED ORGANISMS, METHODS Battelle Energy Alliance, LLC (US) 2010-11-03 — — EP disclosed
WO-2009145945-A9 THERMOPHILIC AND THERMOACIDOPHILIC METABOLISM GENES AND ENZYMES FROM ALICYCLOBACILLUS ACIDOCALDARIUS AND RELATED ORGANISMS, METHODS BATTELLE ENERGY ALLIANCE, LLC (US) 2010-02-04 — — WO disclosed
WO-2009145945-A2 THERMOPHILIC AND THERMOACIDOPHILIC METABOLISM GENES AND ENZYMES FROM ALICYCLOBACILLUS ACIDOCALDARIUS AND RELATED ORGANISMS BATTELLE ENERGY ALLIANCE, LLC (US) 2009-12-03 — — WO disclosed
US-20090269827-A1 Thermophilic and thermoacidophilic metabolism genes and enzymes from alicyclobacillus acidocaldadarius and related organisms, methods BATTELLE ENERGY ALLIANCE, LLC. (US) 2009-10-29 — — US disclosed