Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23928465 | 0.96 | CA2 (0.46) | EPHX2DNM1CA2GPR84FFAR1 | |
| SCHEMBL29180336 | 0.92 | CA2 (0.48) | EPHX2DNM1CA2GPR84FFAR1 | |
| SCHEMBL25319726 | 0.90 | LMNA (0.43) | EPHX2CA2TSHRGPR84FFAR1 | |
| SCHEMBL25317185 | 0.87 | S1PR2 (0.46) | EPHX2CA2GGPS1GPR84FFAR1 | |
| SCHEMBL25698920 | 0.86 | CA2 (0.47) | EPHX2CA2GPR84FFAR1 | |
| SCHEMBL24764590 | 0.86 | CA2 (0.47) | EPHX2CA2GPR84FFAR1 | |
| SCHEMBL25317535 | 0.85 | CA2 (0.40) | EPHX2CA2TSHRGPR84FFAR1 | |
| SCHEMBL20450716 | 0.85 | CA2 (0.50) | EPHX2DNM1CA2GGPS1 | |
| SCHEMBL20450467 | 0.85 | CA2 (0.50) | EPHX2DNM1CA2GGPS1 | |
| SCHEMBL20450713 | 0.85 | CA2 (0.50) | EPHX2DNM1CA2GGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11578031-B2 | Dissymmetric N,N-dialkylamides used particularly for separating uranium(VI) from plutonium(IV), synthesis thereof and uses of same | COMMISSARIAT À L'ÉNERGIE ATOMIQUE ET AUX ÊNERGIES ALTERNATIVES (FR) | 2023-02-14 | — | — | US | disclosed |
| US-20210332002-A1 | DISSYMMETRIC N,N-DIALKYLAMIDES USED PARTICULARLY FOR SEPARATING URANIUM(VI) FROM PLUTONIUM(IV), SYNTHESIS THEREOF AND USES OF SAME | ORANO CYCLE (FR) | 2021-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11578031-B2 | Dissymmetric N,N-dialkylamides used particularly for separating uranium(VI) from plutonium(IV), synthesis thereof and uses of same | NOS2, NOS1, NOS3 | EPHX2 922/4885DNM1 3404/4885CHRM1 290/4885 |
| US-20210332002-A1 | DISSYMMETRIC N,N-DIALKYLAMIDES USED PARTICULARLY FOR SEPARATING URANIUM(VI) FROM PLUTONIUM(IV), SYNTHESIS THEREOF AND USES OF SAME | NOS2, NOS1, NOS3 | EPHX2 922/4885DNM1 3404/4885CHRM1 290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.