Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 1.00 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.82 |
| ▸ | POLB | P06746 | 2/20 | 0.72 |
| ▸ | MEN1 | O00255 | 6/20 | 0.67 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.57 |
| ▸ | RELA | Q04206 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | PLK1 | P53350 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3447906 | 0.91 | PTGS2 (1.00) | KMT2AALDH1A1SMN1; SMN2PTGS2POLB | |
| SCHEMBL28358360 | 0.88 | PTGS2 (0.94) | KMT2AALDH1A1SMN1; SMN2PTGS2POLB | |
| SCHEMBL3506277 | 0.85 | KMT2A (0.74) | KMT2AALDH1A1SMN1; SMN2PTGS2POLB | |
| SCHEMBL16055968 | 0.84 | PTGS2 (0.76) | KMT2AALDH1A1SMN1; SMN2PTGS2POLB | |
| SCHEMBL11244212 | 0.84 | PTGS2 (0.76) | KMT2AALDH1A1SMN1; SMN2PTGS2POLB | |
| SCHEMBL23928527 | 0.84 | PTGS2 (0.80) | KMT2AALDH1A1SMN1; SMN2PTGS2POLB | |
| SCHEMBL11254624 | 0.84 | PTGS2 (0.80) | KMT2AALDH1A1SMN1; SMN2PTGS2POLB | |
| SCHEMBL23392558 | 0.84 | PTGS2 (0.86) | KMT2AALDH1A1SMN1; SMN2PTGS2POLB | |
| SCHEMBL11250330 | 0.84 | POLB (1.00) | KMT2AALDH1A1SMN1; SMN2PTGS2POLB | |
| SCHEMBL10579042 | 0.84 | PTGS2 (0.80) | KMT2AALDH1A1SMN1; SMN2PTGS2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260008754-A1 | N-SUBSTITUTED DERIVATIVES OF L-(L-PHENYL-3-ARYL)-LFF-PYRAZOL-4-YL)METHANAININE, METHOD FOR THEIR PRODUCTION AND THEIR APPLICATIONS | UNIV MEDYCZNY W LUBLINIE (PL) | 2026-01-08 | — | — | US | disclosed |
| US-11548875-B2 | Inhibitor compounds for male contraception | UNIVERSITY OF WASHINGTON (US) | 2023-01-10 | — | — | US | disclosed |
| US-20210332030-A1 | INHIBITOR COMPOUNDS FOR MALE CONTRACEPTION | UNIVERSITY OF WASHINGTON (US) | 2021-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210332030-A1 | INHIBITOR COMPOUNDS FOR MALE CONTRACEPTION | ALDH1A1, ALDH3A1, ALDH16A1 | KMT2A 1384/4885ALDH1A1 1/4885SMN1; SMN2 2873/4885 |
| US-11548875-B2 | Inhibitor compounds for male contraception | ALDH1A1, ALDH3A1, ALDH16A1 | KMT2A 1384/4885ALDH1A1 1/4885SMN1; SMN2 2873/4885 |
| US-20260008754-A1 | N-SUBSTITUTED DERIVATIVES OF L-(L-PHENYL-3-ARYL)-LFF-PYRAZOL-4-YL)METHANAININE, METHOD FOR THEIR PRODUCTION AND THEIR APPLICATIONS | HTR1F, ADH5, HRH4 | KMT2A 1542/4885ALDH1A1 1035/4885SMN1; SMN2 2432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.