SCHEMBL23929009

SCHEMBL23929009

CC(C)(C)OC(=O)N1CCN(c2cccnc2OCc2ccc(Cl)cc2F)CC1

nearest known ligand 0.51

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 7/20 0.51
CYP3A4 P08684 2/20 0.50
CYP3A5 P20815 2/20 0.50
POLB P06746 1/20 0.48
MEN1 O00255 1/20 0.45
NPC1 O15118 1/20 0.45
MAPT P10636 1/20 0.45
KMT2A Q03164 1/20 0.45
FNTA P49354 2/20 0.44
FNTB P49356 2/20 0.44
GRM5 P41594 2/20 0.44
IDE P14735 1/20 0.42
TRPA1 O75762 1/20 0.42
MC4R P32245 1/20 0.42
TRPV1 Q8NER1 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23235736 0.88 GRM5 (0.48) MEN1NPC1MAPTKMT2AGRM5
SCHEMBL23928943 0.85 FNTA (0.48) GPR119CYP3A4CYP3A5POLBMAPT
SCHEMBL24320504 0.84 GPR119 (0.49) GPR119CYP3A4CYP3A5MEN1KMT2A
SCHEMBL28786537 0.83 GPR119 (0.49) GPR119CYP3A4CYP3A5MEN1KMT2A
SCHEMBL28540333 0.83 MEN1 (0.42) MEN1NPC1MAPTKMT2AGRM5
SCHEMBL26913667 0.83 GPR119 (0.57) GPR119CYP3A4CYP3A5MAPT
SCHEMBL30676101 0.82 L3MBTL1 (0.45) MEN1NPC1MAPTKMT2AGRM5
SCHEMBL23235685 0.82 L3MBTL1 (0.45) MEN1NPC1MAPTKMT2AGRM5
SCHEMBL31009243 0.81 GRM1 (0.50) GPR119CYP3A4CYP3A5GRM5
SCHEMBL23928974 0.81 FNTA (0.46) GPR119CYP3A4CYP3A5POLBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250270196-A1 GLP-1 Receptor Agonists and Uses Thereof PFIZER INC. (US) 2025-08-28 US disclosed
US-12331041-B2 GLP-1 receptor agonists and uses thereof PFIZER INC. (US) 2025-06-17 US disclosed
US-20240132483-A1 GLP-1 Receptor Agonists and Uses Thereof PFIZER INC. (US) 2024-04-25 US disclosed
US-11858916-B2 GLP-1 receptor agonists and uses thereof PFIZER INC. (US) 2024-01-02 US disclosed
EP-3806855-B1 GLP-1 RECEPTOR AGONISTS AND USES THEREOF PFIZER (US) 2023-03-01 EP disclosed
US-20210332034-A1 GLP-1 Receptor Agonists and Uses Thereof PFIZER INC. (US) 2021-10-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12331041-B2 GLP-1 receptor agonists and uses thereof GLP1R, GIPR, GCGR GPR119 4/4885CYP3A4 2074/4885CYP3A5 2406/4885
US-11858916-B2 GLP-1 receptor agonists and uses thereof GLP1R, GIPR, GCGR GPR119 4/4885CYP3A4 2074/4885CYP3A5 2406/4885
US-20240132483-A1 GLP-1 Receptor Agonists and Uses Thereof GLP1R, GIPR, GCGR GPR119 4/4885CYP3A4 2074/4885CYP3A5 2406/4885
US-20210332034-A1 GLP-1 Receptor Agonists and Uses Thereof GLP1R, GIPR, GCGR GPR119 4/4885CYP3A4 2074/4885CYP3A5 2406/4885
US-20250270196-A1 GLP-1 Receptor Agonists and Uses Thereof GLP1R, GIPR, GCGR GPR119 4/4885CYP3A4 2074/4885CYP3A5 2406/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.