Water

Water

SCHEMBL239298

CC(C)=C(C)N.O

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL240310 0.94
Ammonia Solution, Strong SCHEMBL8846982 0.89
Bromide SCHEMBL2351020 0.89
Methyl Alcohol SCHEMBL17238762 0.89
Hydrochloric Acid SCHEMBL28189877 0.89
Hydrochloric Acid SCHEMBL28793698 0.89
Hydrochloric Acid SCHEMBL29043749 0.84
Hydrochloric Acid SCHEMBL27684902 0.84
Alcohol SCHEMBL240347 0.77
SCHEMBL742333 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116063625-B Anti-swelling and shrinkage swelling agent, and preparation method and application thereof 中国石油化工股份有限公司 2024-05-07 CN claimed
CN-116063614-A Anti-swelling and shrinkage swelling agent and preparation method and application thereof 中国石油化工股份有限公司 2023-05-05 CN claimed
CN-116063616-A Swelling shrinking agent and preparation method and application thereof 中国石油化工股份有限公司 2023-05-05 CN claimed
CN-116063625-A Anti-swelling and shrinkage swelling agent, and preparation method and application thereof 中国石油化工股份有限公司 2023-05-05 CN claimed
CN-116063615-A Scouring-resistant shrinkage and expansion agent and preparation method and application thereof 中国石油化工股份有限公司 2023-05-05 CN claimed
CN-108148394-B Storage-stable one-component polyurethane prepregs from polyurethane compositions and moldings produced therefrom 赢创运营有限公司 2021-12-28 CN claimed
EP-3330311-B1 STORAGE STABLE 1K-POLYURETHANE-PREPREGS AND MOULDED ARTICLE MADE FROM SAME ON THE BASIS OF A POLYURETHANE COMPOSITION EVONIK OPERATIONS GMBH (DE) 2021-05-05 EP claimed
US-10633519-B2 Storage-stable polyurethane prepregs and mouldings produced therefrom composed of a polyurethane composition with liquid resin components EVONIK OPERATIONS GMBH (DE) 2020-04-28 US claimed
US-10626236-B2 Storage-stable one-component polyurethane prepregs and shaped bodies composed of polyurethane composition that have been produced therefrom EVONIK OPERATIONS GMBH (DE) 2020-04-21 US claimed
CN-108148394-A The stable mono-component polyurethane prepreg of storage from urethane composition and thus obtained formed body 赢创德固赛有限公司 2018-06-12 CN claimed
EP-1334987-B1 Low temperature curable solid powder lacquer compositions containing urethdione groups DEGUSSA (DE) 2006-08-09 EP claimed
US-20050239956-A1 Polyurethane composition which contains an uretdione group DEGUSSA AG (DE) 2005-10-27 US claimed
US-6914115-B2 Low-temperature-curable, solid polyurethane powder coating compositions containing uretdione groups DEGUSSA AG (DE) 2005-07-05 US claimed
US-20050096451-A1 High-reactivity liquid polyurethane systems which contain uretdione groups and can be cured at a low temperature DEGUSSA AG (DE) 2005-05-05 US claimed
US-20050096450-A1 Low temperature curable polyurethane compositions containing uretdione groups DEGUSSA AG (DE) 2005-05-05 US claimed
US-20040219367-A1 Low-temperature-curable, solid polyurethane powder coating compositions containing uretdione groups DEGUSSA AG (DE) 2004-11-04 US claimed
EP-1196784-B1 PROCESS FOR THE QUANTITATIVE DETERMINATION OF ALKALOIDS SUCH AS COCAINE IN A SOLID SAMPLE AND REAGENT FOR USE IN SUCH PROCESS AZIENDA PROVINCIALE PER I SERV (IT) 2003-09-17 EP claimed
US-20030153713-A1 Low-temperature-curable, solid polyurethane powder coating compositions containing uretdione groups DEGUSSA AG (DE) 2003-08-14 US claimed
EP-1196784-A2 PROCESS FOR THE QUANTITATIVE DETERMINATION OF ALKALOIDS SUCH AS COCAINE IN A SOLID SAMPLE AND REAGENT FOR USE IN SUCH PROCESS Azienda Provinciale Per I Servizi Sanitari (IT) 2002-04-17 EP claimed
WO-2001006251-A2 PROCESS FOR THE QUANTITATIVE DETERMINATION OF ALKALOIDS SUCH AS COCAINE IN A SOLID SAMPLE AND REAGENT FOR USE IN SUCH PROCESS AZIENDA PROVINCIALE PER I SERVIZI SANITARI (IT) 2001-01-25 WO claimed