Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.56 |
| ▸ | CA2 | P00918 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA7 | P43166 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | CA6 | P23280 | 2/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL25435080 | 0.91 | LMNA (0.64) | CA1CA2ALDH1A1TSHRTP53 | |
| SCHEMBL2393266 | 0.91 | LMNA (0.52) | CA1CA2ALDH1A1TSHRF2 | |
| SCHEMBL11512239 | 0.85 | TSHR (0.67) | CA1CA2ALDH1A1TSHRTP53 | |
| SCHEMBL22832 | 0.84 | LMNA (0.73) | ALDH1A1TSHRTP53SMN1; SMN2F2 | |
| Benzene SCHEMBL28159757 | 0.84 | LMNA (0.73) | ALDH1A1TSHRTP53SMN1; SMN2F2 | |
| SCHEMBL20953380 | 0.84 | CA1 (0.48) | CA1CA2ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL19578373 | 0.82 | HPGD (0.52) | CA1CA2ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL5493258 | 0.82 | CA1 (0.45) | CA1CA2ALDH1A1TSHRF2 | |
| SCHEMBL6341742 | 0.82 | CA1 (0.68) | CA1CA2ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL28241417 | 0.82 | LMNA (0.70) | ALDH1A1TSHRTP53SMN1; SMN2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10364251-B2 | Polyesters from assymetrical monomers based upon bisanhydrohexitols | NEW JERSEY INSTITUTE OF TECHNOLOGY (US) | 2019-07-30 | — | — | US | disclosed |
| US-20170210750-A1 | Polyesters From Assymetrical Monomers Based Upon Bisanhydrohexitols | NEW JERSEY INSTITUTE OF TECHNOLOGY | 2017-07-27 | — | — | US | disclosed |
| US-9580544-B2 | Polyesters from asymetrical monomers based upon bisanhydrohexitols | NEW JERSEY INSTITUTE OF TECHNOLOGY (US) | 2017-02-28 | — | — | US | disclosed |
| EP-2547708-A2 | NEW POLYESTERS FROM ASYMMETRICAL MONOMERS BASED UPON BISANHYDROHEXITOLS | New Jersey Institute of Technology (US) | 2013-01-23 | — | — | EP | disclosed |
| US-20110237757-A1 | Polyesters From Assymetrical Monomers Based Upon Bisanhydrohexitols | IOWA CORN PROMOTION BOARD (US) | 2011-09-29 | — | — | US | disclosed |
| WO-2011116275-A2 | NEW POLYESTERS FROM ASYMMETRICAL MONOMERS BASED UPON BISANHYDROHEXITOLS | NEW JERSEY INSTITUTE OF TECHNOLOGY (US) | 2011-09-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10364251-B2 | Polyesters from assymetrical monomers based upon bisanhydrohexitols | ACMSD, AKR1C2, ALDOA | CA1 2423/4885CA2 1086/4885ALDH1A1 1035/4885 |
| US-20110237757-A1 | Polyesters From Assymetrical Monomers Based Upon Bisanhydrohexitols | ADSL, FHIT, ADSS2 | CA1 2807/4885CA2 1823/4885ALDH1A1 696/4885 |
| US-20170210750-A1 | Polyesters From Assymetrical Monomers Based Upon Bisanhydrohexitols | ADSL, FHIT, ADSS2 | CA1 2807/4885CA2 1823/4885ALDH1A1 696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.