SCHEMBL23933303

SCHEMBL23933303

COC(=O)C1C(c2ccc(F)c(Cl)c2)C1(Cl)Cl

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.40
KMT2A Q03164 5/20 0.40
MAPT P10636 3/20 0.40
NPC1 O15118 2/20 0.40
HTT P42858 2/20 0.40
RAB9A P51151 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
LMNA P02545 2/20 0.39
CASP3 P42574 1/20 0.39
SENP7 Q9BQF6 1/20 0.39
TAS1R3 Q7RTX0 1/20 0.38
TAS1R1 Q7RTX1 1/20 0.38
TAS1R2 Q8TE23 1/20 0.38
TSHR P16473 1/20 0.38
ALDH1A1 P00352 1/20 0.37
RECQL P46063 1/20 0.37
SLC9A1 P19634 1/20 0.37
SLC6A3 Q01959 2/20 0.37
SLC6A4 P31645 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23961598 1.00 MEN1 (0.40) MEN1KMT2AMAPTNPC1HTT
SCHEMBL23961555 1.00 MEN1 (0.40) MEN1KMT2AMAPTNPC1HTT
SCHEMBL21079070 0.89 MEN1 (0.36) MEN1KMT2AMAPTNPC1HTT
SCHEMBL23961568 0.87 SLC6A3 (0.47) SLC6A3SLC6A4
SCHEMBL30138625 0.87 SLC6A3 (0.47) SLC6A3SLC6A4
SCHEMBL23933305 0.87 SLC6A3 (0.47) SLC6A3SLC6A4
SCHEMBL25870352 0.86 SLC9A1 (0.51) MEN1KMT2AMAPTHTTLMNA
SCHEMBL20076620 0.85 SLC9A1 (0.40) MEN1KMT2AMAPTNPC1HTT
SCHEMBL23961569 0.83 MEN1 (0.38) MEN1KMT2AMAPTLMNATAS1R3
SCHEMBL23933318 0.83 MEN1 (0.38) MEN1KMT2AMAPTLMNATAS1R3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4139272-A1 PROCESSES RELATED TO FORMATION OF ARYLCYCLOPROPYL CARBOXYLIC ACIDS Corteva Agriscience LLC (US) 2023-03-01 EP claimed
CN-115485260-A Processes related to the formation of aryl cyclopropyl carboxylic acids 科迪华农业科技有限责任公司 2022-12-16 CN claimed
WO-2021216629-A1 PROCESSES RELATED TO FORMATION OF ARYLCYCLOPROPYL CARBOXYLIC ACIDS CORTEVA AGRISCIENCE LLC (US) 2021-10-28 WO claimed
US-20230220427-A1 PROCESSES RELATED TO FORMATION OF ARYLCYCLOPROPYL CARBOXYLIC ACIDS CORTEVA AGRISCIENCE LLC (US) 2023-07-13 US disclosed
EP-4139272-A1 PROCESSES RELATED TO FORMATION OF ARYLCYCLOPROPYL CARBOXYLIC ACIDS Corteva Agriscience LLC (US) 2023-03-01 EP disclosed
CN-115485260-A Processes related to the formation of aryl cyclopropyl carboxylic acids 科迪华农业科技有限责任公司 2022-12-16 CN disclosed
WO-2021216629-A1 PROCESSES RELATED TO FORMATION OF ARYLCYCLOPROPYL CARBOXYLIC ACIDS CORTEVA AGRISCIENCE LLC (US) 2021-10-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230220427-A1 PROCESSES RELATED TO FORMATION OF ARYLCYCLOPROPYL CARBOXYLIC ACIDS DDT, PCCA, DDC MEN1 4793/4885KMT2A 3122/4885MAPT 4212/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.