SCHEMBL23933318

SCHEMBL23933318

COC(=O)C1C(c2ccc(F)c(C(F)(F)F)c2)C1(Cl)Cl

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.38
KMT2A Q03164 4/20 0.38
TAS1R3 Q7RTX0 2/20 0.38
TAS1R1 Q7RTX1 2/20 0.38
TAS1R2 Q8TE23 2/20 0.38
MAPT P10636 2/20 0.38
KCNN4 O15554 2/20 0.37
LMNA P02545 2/20 0.37
AR P10275 1/20 0.36
ADRA2A P08913 1/20 0.36
CHRNB2 P17787 1/20 0.36
ADRA2C P18825 1/20 0.36
CHRNB4 P30926 1/20 0.36
CHRNA3 P32297 1/20 0.36
CHRNA7 P36544 1/20 0.36
CHRNA4 P43681 1/20 0.36
TMEM97 Q5BJF2 1/20 0.36
GRM4 Q14833 1/20 0.36
SLC9A1 P19634 2/20 0.35
ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23961569 1.00 MEN1 (0.38) MEN1KMT2ATAS1R3TAS1R1TAS1R2
SCHEMBL30138574 1.00 MEN1 (0.38) MEN1KMT2ATAS1R3TAS1R1TAS1R2
SCHEMBL21021644 0.87 ADRA2A (0.39) MEN1KMT2ATAS1R3TAS1R1TAS1R2
SCHEMBL18146735 0.84 NOTUM (0.40) MEN1KMT2ATAS1R3TAS1R1TAS1R2
SCHEMBL20901183 0.84 NOTUM (0.40) MEN1KMT2ATAS1R3TAS1R1TAS1R2
SCHEMBL18146734 0.84 NOTUM (0.40) MEN1KMT2ATAS1R3TAS1R1TAS1R2
SCHEMBL18146739 0.84 NOTUM (0.40) MEN1KMT2ATAS1R3TAS1R1TAS1R2
SCHEMBL29414010 0.84 NOTUM (0.40) MEN1KMT2ATAS1R3TAS1R1TAS1R2
SCHEMBL20076634 0.83 SLC9A1 (0.40) MEN1KMT2ATAS1R3TAS1R1TAS1R2
SCHEMBL30739761 0.83 SLC9A1 (0.40) MEN1KMT2ATAS1R3TAS1R1TAS1R2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4139272-A1 PROCESSES RELATED TO FORMATION OF ARYLCYCLOPROPYL CARBOXYLIC ACIDS Corteva Agriscience LLC (US) 2023-03-01 EP claimed
CN-115485260-A Processes related to the formation of aryl cyclopropyl carboxylic acids 科迪华农业科技有限责任公司 2022-12-16 CN claimed
WO-2021216629-A1 PROCESSES RELATED TO FORMATION OF ARYLCYCLOPROPYL CARBOXYLIC ACIDS CORTEVA AGRISCIENCE LLC (US) 2021-10-28 WO claimed
US-20230220427-A1 PROCESSES RELATED TO FORMATION OF ARYLCYCLOPROPYL CARBOXYLIC ACIDS CORTEVA AGRISCIENCE LLC (US) 2023-07-13 US disclosed
EP-4139272-A1 PROCESSES RELATED TO FORMATION OF ARYLCYCLOPROPYL CARBOXYLIC ACIDS Corteva Agriscience LLC (US) 2023-03-01 EP disclosed
CN-115485260-A Processes related to the formation of aryl cyclopropyl carboxylic acids 科迪华农业科技有限责任公司 2022-12-16 CN disclosed
WO-2021216629-A1 PROCESSES RELATED TO FORMATION OF ARYLCYCLOPROPYL CARBOXYLIC ACIDS CORTEVA AGRISCIENCE LLC (US) 2021-10-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230220427-A1 PROCESSES RELATED TO FORMATION OF ARYLCYCLOPROPYL CARBOXYLIC ACIDS DDT, PCCA, DDC MEN1 4793/4885KMT2A 3122/4885TAS1R3 3272/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.