Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.71 |
| ▸ | SLC40A1 | Q9NP59 | 5/20 | 0.69 |
| ▸ | GLO1 | Q04760 | 3/20 | 0.69 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.69 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | RELA | Q04206 | 6/20 | 0.57 |
| ▸ | NFKBIA | P25963 | 6/20 | 0.57 |
| ▸ | SQSTM1 | Q13501 | 1/20 | 0.56 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.56 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MITF | O75030 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26053588 | 0.83 | KMT2A (1.00) | TDP1KMT2AMEN1SLC40A1GLO1 | |
| SCHEMBL18889904 | 0.83 | KMT2A (0.71) | TDP1KMT2AMEN1SLC40A1GLO1 | |
| SCHEMBL6984645 | 0.82 | SLC40A1 (1.00) | TDP1KMT2AMEN1SLC40A1GLO1 | |
| SCHEMBL23933986 | 0.81 | KMT2A (0.74) | TDP1KMT2AMEN1SLC40A1GLO1 | |
| SCHEMBL23934034 | 0.79 | KMT2A (0.76) | TDP1KMT2AMEN1SLC40A1GLO1 | |
| SCHEMBL23934032 | 0.79 | KMT2A (0.76) | TDP1KMT2AMEN1SLC40A1GLO1 | |
| SCHEMBL22578645 | 0.78 | KMT2A (0.74) | TDP1KMT2AMEN1SLC40A1GLO1 | |
| SCHEMBL28109026 | 0.77 | KEAP1 (0.72) | TDP1KMT2AMEN1LMNANPSR1 | |
| SCHEMBL17552186 | 0.76 | KMT2A (0.74) | KMT2AMEN1LMNAKDM4ENPC1 | |
| SCHEMBL29831356 | 0.76 | KMT2A (0.74) | KMT2AMEN1LMNAKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210323924-A1 | QUINOLINE SULFONAMIDES USEFUL TO TREAT DISEASE | DAHL RUSSELL (US) | 2021-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210323924-A1 | QUINOLINE SULFONAMIDES USEFUL TO TREAT DISEASE | CLN6, NDUFS3, NDUFS2 | TDP1 662/4885KMT2A 2019/4885MEN1 2804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.