Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 4/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.35 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | GFRA2 | O00451 | 1/20 | 0.33 |
| ▸ | GFRA3 | O60609 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | PPIB | P23284 | 1/20 | 0.32 |
| ▸ | PPIA | P62937 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984887 | 0.78 | PIN1 (0.47) | PIN1PDPK1KCNQ2ANO1 | |
| SCHEMBL19984933 | 0.77 | PIN1 (0.40) | PIN1PDPK1KCNQ2ANO1GFRA2 | |
| SCHEMBL19984930 | 0.72 | NFE2L2 (0.39) | PIN1PDPK1KCNQ2PPIBPPIA | |
| SCHEMBL19984921 | 0.72 | NFE2L2 (0.39) | PIN1PDPK1KCNQ2PPIBPPIA | |
| SCHEMBL21538767 | 0.71 | PIN1 (0.52) | PIN1PDPK1KCNQ2ANO1PDE4A | |
| SCHEMBL10469672 | 0.69 | PIN1 (0.54) | PIN1PDPK1KCNQ2ANO1PDE4A | |
| SCHEMBL8301042 | 0.69 | PIN1 (0.47) | PIN1KCNQ2ANO1MTNR1AMTNR1B | |
| SCHEMBL23934491 | 0.69 | CCR2 (0.35) | PIN1ANO1GFRA2GFRA3PPIB | |
| SCHEMBL8848989 | 0.67 | PIN1 (0.58) | PIN1PDPK1KCNQ2ANO1MTNR1A | |
| SCHEMBL4742598 | 0.67 | PIN1 (0.58) | PIN1PDPK1KCNQ2ANO1MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512843-B1 | PLANT GROWTH REGULATOR COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-10-20 | — | — | EP | disclosed |