Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 4/20 | 0.47 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.38 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19985038 | 0.91 | PIN1 (0.46) | PIN1ANO1MEN1KMT2AKCNQ2 | |
| SCHEMBL21538694 | 0.83 | ALDH1A1 (0.43) | MEN1KMT2AL3MBTL1ALDH1A1FFAR1 | |
| SCHEMBL7419740 | 0.82 | PIN1 (0.51) | PIN1ANO1KCNQ2L3MBTL1ALDH1A1 | |
| SCHEMBL21538768 | 0.82 | ANO1 (0.41) | PIN1ANO1MEN1KMT2AL3MBTL1 | |
| SCHEMBL4720088 | 0.81 | PIN1 (0.52) | PIN1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL23934559 | 0.81 | PIN1 (0.38) | PIN1ANO1MEN1KMT2AKCNQ2 | |
| SCHEMBL19985047 | 0.81 | PIN1 (0.38) | PIN1ANO1MEN1KMT2AKCNQ2 | |
| SCHEMBL19984944 | 0.79 | NFE2L2 (0.38) | PIN1ANO1L3MBTL1ALDH1A1MAPT | |
| SCHEMBL19984922 | 0.79 | PIN1 (0.37) | PIN1ANO1L3MBTL1ALDH1A1MAPT | |
| SCHEMBL19985034 | 0.77 | MEN1 (0.41) | MEN1KMT2AL3MBTL1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661273-B1 | Indane derivatives and processes for preparing the same | TANABE SEIYAKU CO (JP) | 1999-05-19 | — | — | EP | disclosed |
| US-5686452-A | PROTECTING FROM ENDOTOXIN SHOCK; TREATMENT OF NEPHRITIS | TANABE SEIYAKU CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |
| CN-1107844-A | Indane derivative, processes for preparing the same and synthetic intermediate of the same | TANABE SEIYAKU CO (JP) | 1995-09-06 | — | — | CN | disclosed |
| EP-0661273-A1 | Indane derivative and processes for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1995-07-05 | — | — | EP | disclosed |