Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25654057 | 0.87 | ALOX15 (0.31) | KDM4EALOX15 | |
| SCHEMBL23934675 | 0.82 | THRB (0.33) | KDM4EALOX15 | |
| SCHEMBL20327290 | 0.79 | ALDH1A1 (0.35) | KDM4EALOX15 | |
| SCHEMBL21848620 | 0.76 | THRB (0.34) | KDM4EALOX15 | |
| SCHEMBL23739497 | 0.74 | THRB (0.33) | KDM4EALOX15 | |
| SCHEMBL23739760 | 0.74 | ALOX15 (0.34) | KDM4EALOX15 | |
| SCHEMBL7671030 | 0.74 | KDM4E (0.39) | KDM4EALOX15 | |
| SCHEMBL22511600 | 0.73 | UTS2R (0.32) | KDM4EALOX15 | |
| SCHEMBL22300324 | 0.73 | MAPT (0.34) | KDM4EALOX15 | |
| SCHEMBL18639839 | 0.73 | KDM4E (0.39) | KDM4EALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3896062-A1 | ISOINDOLINE COMPOUND, AND PREPARATION METHOD, PHARMACEUTICAL COMPOSITION, AND APPLICATION OF ISOINDOLINE COMPOUND | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2021-10-20 | — | — | EP | disclosed |