Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL853546 | 0.86 | MAPT (0.50) | KMT2ANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL2393841 | 0.85 | MAPT (0.51) | KMT2ANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL2393595 | 0.85 | LMNA (0.51) | KMT2ANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL2398594 | 0.82 | MAPT (0.67) | KMT2ANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL9786979 | 0.81 | NPC1 (0.44) | KMT2ANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL830740 | 0.81 | KMT2A (0.60) | KMT2ANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL5770727 | 0.80 | L3MBTL1 (0.60) | KMT2ANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL29620411 | 0.79 | L3MBTL1 (0.58) | KMT2ANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL14499026 | 0.79 | KMT2A (0.57) | KMT2ANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL14075278 | 0.79 | MEN1 (0.71) | KMT2ANPC1RAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2836497-B1 | CATALYST COMPOUNDS | UNIV LIVERPOOL (GB) | 2016-03-23 | — | — | EP | disclosed |
| US-9212199-B2 | Catalyst compounds | THE UNIVERSITY OF LIVERPOOL (GB) | 2015-12-15 | — | — | US | disclosed |
| US-9212199-B2 | Catalyst compounds | THE UNIVERSITY OF LIVERPOOL (GB) | 2015-12-15 | — | — | US | disclosed |
| US-20150080592-A1 | CATALYST COMPOUNDS | THE UNIVERSITY OF LIVERPOOL (GB) | 2015-03-19 | — | — | US | disclosed |
| US-20150080592-A1 | CATALYST COMPOUNDS | THE UNIVERSITY OF LIVERPOOL (GB) | 2015-03-19 | — | — | US | disclosed |
| WO-2013153407-A1 | CATALYST COMPOUNDS | THE UNIVERSITY OF LIVERPOOL (GB) | 2013-10-17 | — | — | WO | disclosed |
| US-8012901-B1 | Method of synthesizing enantiopure mexiletine analogues and novel β-thiophenoxy and pyridyl ethers | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-09-06 | — | — | US | disclosed |
| US-8012901-B1 | Method of synthesizing enantiopure mexiletine analogues and novel β-thiophenoxy and pyridyl ethers | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150080592-A1 | CATALYST COMPOUNDS | IDH3B, IDH2, NQO1 | KMT2A 1132/4885NPC1 2868/4885RAB9A 857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.