Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23937754 | 0.82 | HRH4 (0.34) | NOTUMHRH4 | |
| SCHEMBL20674079 | 0.77 | PDE2A (0.40) | FTOSMN1; SMN2 | |
| SCHEMBL21440750 | 0.75 | — | — | |
| SCHEMBL23937755 | 0.75 | FTO (0.36) | FTOLMNA | |
| SCHEMBL23937757 | 0.72 | PKM (0.35) | FTOLMNA | |
| SCHEMBL23937851 | 0.72 | TLR7 (0.35) | HTTSMN1; SMN2NOTUMHRH4 | |
| SCHEMBL18711826 | 0.71 | HRH4 (0.36) | NOTUMHRH4 | |
| SCHEMBL31514720 | 0.69 | GAA (0.36) | NOTUMHRH4 | |
| SCHEMBL28904493 | 0.69 | GAA (0.36) | NOTUMHRH4 | |
| SCHEMBL19341247 | 0.69 | HRH4 (0.51) | NOTUMHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3399968-B1 | SELECTIVE INHIBITORS OF CLINICALLY IMPORTANT MUTANTS OF THE EGFR TYROSINE KINASE | CS PHARMATECH LTD (KY) | 2021-10-20 | — | — | EP | disclosed |